J Pathol Transl Med.  2019 Sep;53(5):341-344. 10.4132/jptm.2019.06.05.

Liquid-Based Cytology Features of Papillary Squamotransitional Cell Carcinoma of the Uterine Cervix

Affiliations
  • 1Department of Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
  • 2Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. haeryoung.kim@snu.ac.kr
  • 3Department of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
  • 4Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

Abstract

No abstract available.


MeSH Terms

Cervix Uteri*
Female

Figure

  • Fig. 1. Colposcopy reveals a friable papillary mass in the cervical canal.

  • Fig. 2. Liquid-based cytology findings. (A) Low-power magnification shows some scattered hyperchromatic crowded groups and abundant individually scattered cells. (B) A papillary cluster (center) is lined by small neoplastic cells with round-to-oval nuclei and minimal nuclear atypia. (C) The scattered neoplastic cells demonstrate similar features, with eccentrically located, round-to-oval nuclei. Long cytoplasmic processes are seen in some neoplastic cells (“cercariform” cells) at the edge of papillary fragments (C, inset). A mitotic figure is seen (arrow). (D) A high-grade squamous intraepithelial lesion cell with coarse chromatin and irregular nuclear membrane (center) is seen among the scattered low-grade urothelial carcinoma-like cells. (E, F) Dyskeratotic cells and focal koilocytotic atypia are occasionally seen.

  • Fig. 3. Histological findings. (A) Low-power view demonstrates papillary structures with fibrovascular cores. (B) The papillae are mostly lined by urothelial-like cells. (C, D) Focal areas of keratinization (C) and koilocytotic atypia (D) are seen in the surfaces of the papillae.


Reference

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