Ann Surg Treat Res.  2019 Oct;97(4):194-201. 10.4174/astr.2019.97.4.194.

Efficacy of biofeedback therapy for objective improvement of pelvic function in low anterior resection syndrome

Affiliations
  • 1Department of Surgery, Chungnam National University College of Medicine, Daejeon, Korea. jkim@cnu.ac.kr

Abstract

PURPOSE
There is no established treatment of choice for low anterior resection syndrome (LARS). To evaluate the efficacy of biofeedback therapy for objective improvement of pelvic function in LARS, we performed the present study.
METHODS
The primary endpoint was the change of Wexner score. Consenting patients between 20 and 80 years old with major LARS at least 2 months after sphincter preserving proctectomy for rectal cancer were enrolled. After recommendation of biofeedback therapy, patients who accept it were enrolled in the biofeedback group and patients who refuse were enrolled in the control group. Initial and follow-up evaluations were performed and analyzed.
RESULTS
Fifteen and sixteen patients were evaluated in the control group and the biofeedback group, respectively. There was no statistically significant difference of LARS score between both groups. Decrease in Wexner score and increase in rectal capacity were significantly higher in the biofeedback group (odds ratio [OR], 5.386; 95% confidence interval [CI], 1.194-24.287; P = 0.028 and OR, 1.061; 95% CI, 1.002-1.123; P = 0.042).
CONCLUSION
Biofeedback therapy was superior for objective improvement of pelvic function to observation in LARS. It can be considered to induce more rapid improvement of major LARS.

Keyword

Fecal incontinence; Manometry; Postoperative complications; Rectal neoplasm; Rehabilitation

MeSH Terms

Biofeedback, Psychology*
Fecal Incontinence
Follow-Up Studies
Humans
Manometry
Postoperative Complications
Rectal Neoplasms
Rehabilitation

Figure

  • Fig. 1 The low anterior resection syndrome score (LARS score).

  • Fig. 2 Flow-chart. LARS, low anterior resection syndrome; WS, Wexner score; NBM, number of bowel movement.

  • Fig. 3 The Wexner score (The translated version into the native language was used).


Reference

1. Emmertsen KJ, Laurberg S. Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer. Ann Surg. 2012; 255:922–928.
2. Martellucci J. Low anterior resection syndrome: a treatment algorithm. Dis Colon Rectum. 2016; 59:79–82.
3. Kupsch J, Jackisch T, Matzel KE, Zimmer J, Schreiber A, Sims A, et al. Outcome of bowel function following anterior resection for rectal cancer-an analysis using the low anterior resection syndrome (LARS) score. Int J Colorectal Dis. 2018; 33:787–798.
Article
4. Warschkow R, Ebinger SM, Brunner W, Schmied BM, Marti L. Survival after abdominoperineal and sphincter-preserving resection in nonmetastatic rectal cancer: a population-based time-trend and propensity score-matched SEER analysis. Gastroenterol Res Pract. 2017; 2017:6058907.
Article
5. Dahlberg M, Glimelius B, Graf W, Pahlman L. Preoperative irradiation affects functional results after surgery for rectal cancer: results from a randomized study. Dis Colon Rectum. 1998; 41:543–549.
6. Rosen H, Robert-Yap J, Tentschert G, Lechner M, Roche B. Transanal irrigation improves quality of life in patients with low anterior resection syndrome. Colorectal Dis. 2011; 13:e335–e338.
Article
7. Pucciani F, Ringressi MN, Redditi S, Masi A, Giani I. Rehabilitation of fecal incontinence after sphincter-saving surgery for rectal cancer: encouraging results. Dis Colon Rectum. 2008; 51:1552–1558.
Article
8. Kim KH, Yu CS, Yoon YS, Yoon SN, Lim SB, Kim JC. Effectiveness of biofeedback therapy in the treatment of anterior resection syndrome after rectal cancer surgery. Dis Colon Rectum. 2011; 54:1107–1113.
Article
9. Lin KY, Granger CL, Denehy L, Frawley HC. Pelvic floor muscle training for bowel dysfunction following colorectal cancer surgery: a systematic review. Neurourol Urodyn. 2015; 34:703–712.
Article
10. de Miguel M, Oteiza F, Ciga MA, Armendariz P, Marzo J, Ortiz H. Sacral nerve stimulation for the treatment of faecal incontinence following low anterior resection for rectal cancer. Colorectal Dis. 2011; 13:72–77.
Article
11. Schwandner O. Sacral neuromodulation for fecal incontinence and “low anterior resection syndrome” following neoadjuvant therapy for rectal cancer. Int J Colorectal Dis. 2013; 28:665–669.
Article
12. Laforest A, Bretagnol F, Mouazan AS, Maggiori L, Ferron M, Panis Y. Functional disorders after rectal cancer resection: does a rehabilitation programme improve anal continence and quality of life? Colorectal Dis. 2012; 14:1231–1237.
Article
13. Visser WS, Te Riele WW, Boerma D, van Ramshorst B, van Westreenen HL. Pelvic floor rehabilitation to improve functional outcome after a low anterior resection: a systematic review. Ann Coloproctol. 2014; 30:109–114.
Article
14. Brown CJ, Fenech DS, McLeod RS. Reconstructive techniques after rectal resection for rectal cancer. Cochrane Database Syst Rev. 2008; (2):CD006040.
Article
15. Chen TY, Wiltink LM, Nout RA, Meershoek-Klein Kranenbarg E, Laurberg S, Marijnen CA, et al. Bowel function 14 years after preoperative short-course radiotherapy and total mesorectal excision for rectal cancer: report of a multicenter randomized trial. Clin Colorectal Cancer. 2015; 14:106–114.
Article
16. Williamson ME, Lewis WG, Finan PJ, Miller AS, Holdsworth PJ, Johnston D. Recovery of physiologic and clinical function after low anterior resection of the rectum for carcinoma: myth or reality? Dis Colon Rectum. 1995; 38:411–418.
17. Pucciarelli S, Del Bianco P, Efficace F, Toppan P, Serpentini S, Friso ML, et al. Health-related quality of life, faecal continence and bowel function in rectal cancer patients after chemoradiotherapy followed by radical surgery. Support Care Cancer. 2010; 18:601–608.
Article
18. Farouk R, Duthie GS, Lee PW, Monson JR. Endosonographic evidence of injury to the internal anal sphincter after low anterior resection: long-term follow-up. Dis Colon Rectum. 1998; 41:888–891.
19. Bryant CL, Lunniss PJ, Knowles CH, Thaha MA, Chan CL. Anterior resection syndrome. Lancet Oncol. 2012; 13:e403–e408.
Article
Full Text Links
  • ASTR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr