Infect Chemother.  2019 Sep;51(3):305-309. 10.3947/ic.2019.51.3.305.

Modified Measles in an Anti-Measles Immunoglobulin G-negative Healthcare Worker who had Received Two Doses of Measles-Containing Vaccine

Affiliations
  • 1Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Korea. yacsog@schmc.ac.kr
  • 2Office for Infection Control, Soonchunhyang University Cheonan Hospital, Korea.

Abstract

To date, documentation of two doses of measles-containing vaccine (MCV) has been accepted as confirmation of measles immunity among healthcare workers (HCWs). However, we encountered measles in an HCW who had received two doses of MCV. A patient with measles was admitted to our hospital. Among 62 exposed HCWs, one nurse who had previously received two doses of MCV was shown to be negative for anti-measles immunoglobulin G (IgG), and was confirmed to have measles 14 days after exposure. Based on this experience, we suggest that all HCWs should be tested for anti-measles IgG to confirm their immunity to measles.

Keyword

Measles; Measles vaccine; Patient-to-professional transmission; Measles-mumps-rubella vaccine

MeSH Terms

Delivery of Health Care*
Humans
Immunoglobulin G
Immunoglobulins*
Infectious Disease Transmission, Patient-to-Professional
Measles Vaccine
Measles*
Measles-Mumps-Rubella Vaccine
Immunoglobulin G
Immunoglobulins
Measles Vaccine
Measles-Mumps-Rubella Vaccine
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