Ann Dermatol.  2018 Aug;30(4):503-504. 10.5021/ad.2018.30.4.503.

Paraneoplastic Generalized Granuloma Annulare in a Patient with Hepatocellular Carcinoma

• Cho SI
• Yu DA
• Lee JH
• Cho KH
• Mun JH

• KMID: 2457540
• DOI: http://doi.org/10.5021/ad.2018.30.4.503

Abstract

No abstract available.

MeSH Terms

Carcinoma, Hepatocellular*
Granuloma Annulare*
Granuloma*
Humans

Figure

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  Fig. 1 (A) Multiple disseminated erythematous papules and plaques on the back. (B) Well-demarcated erythematous plaque on the wrist.

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  Fig. 2 (A) Skin biopsy showing normal epidermis with palisaded granulomatous inflammation in the upper dermis (H&E, ×40). (B) Palisading histiocytes surrounding collagen bundles (H&E, ×100).

Reference

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2. Mestre T, Rodrigues AM, Cardoso J. Disseminated granuloma annulare and hepatocellular carcinoma: association orcoincidence? BMJ Case Rep. 2014; DOI: 10.1136/bcr-2014-205883.

3. Yun JH, Lee JY, Kim MK, Seo YJ, Kim MH, Cho KH, et al. Clinical and pathological features of generalized granuloma annulare with their correlation: a retrospective multicenter study in Korea. Ann Dermatol. 2009; 21:113–119.

4. Alsahafi M, AlJasser MI, Kalia S, Yang HM, Ramji A. Chronic hepatitis with liver granulomas in a patient with granuloma annulare: a case report and review of the literature. Case Rep Gastrointest Med. 2017; 2017:8768529.

5. Chiu ML, Tang MB. Generalized granuloma annulare associated with gastrointestinal stromal tumour: case report and review of clinical features and management. Clin Exp Dermatol. 2008; 33:469–471.