Korean J Blood Transfus.  2019 Aug;30(2):163-167. 10.17945/kjbt.2019.30.2.163.

Investigation of the Association of HCV or HIV Markers in Non-Discriminated Blood Donations

• Kang J
• Shin S
• Kang JW
• Seo YI
• Min H
• Kim M

• KMID: 2457175
• DOI: http://doi.org/10.17945/kjbt.2019.30.2.163

Abstract

HBV core antibody and surface antibody test are currently conducted for those donors showing non-discriminated reactive (NDR) results on a nucleic acid amplification test (NAT) as a blood donor screening assay. It is necessary to investigate the relationship with HCV or HIV in the donors showing NDR results. From June 12th, 2012 to December 31st, 2018, 0.05% (9,020/17,798,461) donors showed NDR results on a NAT. Among the donors showing NDR results, 17 and 18 donors showed positive results on serological assay of HCV and HIV, respectively. 23 donors with NDR results showed positive results on the serological assay or NAT for HCV or HIV on the following donation. Further study and more accumulated data are required because it may be difficult to find the cause of NDR results by the current serological assay that is used for screening blood donors.

Keyword

Non-discriminated reactive; Nucleic acid amplification test; HCV; HIV

MeSH Terms

Blood Donors*
HIV*
Humans
Mass Screening
Nucleic Acid Amplification Techniques
Tissue Donors