Obstet Gynecol Sci.  2019 Sep;62(5):299-306. 10.5468/ogs.2019.62.5.299.

Management of disseminated intravascular coagulation associated with placental abruption and measures to improve outcomes

• Takeda J
• Takeda S

• KMID: 2456824
• DOI: http://doi.org/10.5468/ogs.2019.62.5.299

Abstract

Placental abruption is a condition that should be carefully considered in perinatal management because it is associated with serious events in both the mother and neonate, such as intrauterine fetal death, cerebral palsy, obstetric critical bleeding, and uncontrollable bleeding. The concomitant presence of disseminated intravascular coagulation (DIC) more easily causes critical bleeding that may necessitate hysterectomy or multi-organ failure resulting in maternal death. Therefore, early management should be provided to prevent progression to serious conditions by performing both hemostatic procedures and DIC treatment. To take measures to improve the outcomes in both the mother and neonate, health guidance for pregnant women, early diagnosis, early treatment, development of the emergency care system, and provision of a system for transport to higher-level medical institutions should be implemented.

Keyword

Cerebral palsy; Disseminated intravascular coagulation; Fibrinogen; Obstetric surgical procedures; Placental abruption

MeSH Terms

Abruptio Placentae*
Cerebral Palsy
Dacarbazine
Disseminated Intravascular Coagulation*
Early Diagnosis
Emergency Medical Services
Female
Fetal Death
Fibrinogen
Hemorrhage
Humans
Hysterectomy
Infant, Newborn
Maternal Death
Mothers
Obstetric Surgical Procedures
Pregnancy
Pregnant Women
Dacarbazine
Fibrinogen

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