Ann Dermatol.  2019 Aug;31(Suppl):S56-S58. 10.5021/ad.2019.31.S.S56.

Possible Involvement of Cancer Producing Thymic Stromal Lymphopoietin as an Initiator of Papuloerythroderma of Ofuji

• Ueo D
• Yoshizumi
• Shirasaka
• Kitagawa M
• Ohshima K
• Higashi S
• Fujiwara S
• Hatano Y

• KMID: 2456680
• DOI: http://doi.org/10.5021/ad.2019.31.S.S56

Abstract

No abstract available.

Figure

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  Fig. 1 (A) Pruritic, flat-topped, red papules coalesced into an erythroderma-like lesion, representing deck-chair sign (DCS). (B) The entire circumference of the tumor in the rectosigmoidal colon. (C) DCS finally resolved after two years of endoscopic resection and never appeared since then. We received the patient's consent form about publishing all photographic materials.

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  Fig. 2 (A) Some lymphocytes were CCR4 positive of the infiltrating lymphocytes in the upper dermis (CCR4, ×400). (B) CCR4 were partly positive in the infiltrating lymphocytes around the colorectal cancer cells (CCR4, ×400). (C) Epidermal cells from the lesional skin were mildly positive for anti-TSLP antibody (TSLP, ×400). (D) Colorectal cancer cells were moderately positive for anti-TSLP antibody (TSLP, ×400). TSLP: thymic stromal lymphopoietin.

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