J Korean Assoc Oral Maxillofac Surg.  2019 Aug;45(4):180-185. 10.5125/jkaoms.2019.45.4.180.

Huge central intravascular papillary endothelial hyperplasia of the mandible: a case report and review of the literature

• Mirmohammadsadeghi H
• Mashhadiabbas F
• Latifi F

• KMID: 2456035
• DOI: http://doi.org/10.5125/jkaoms.2019.45.4.180

Abstract

Masson's tumor or intravascular papillary endothelial hyperplasia is an inflammatory soft tissue lesion that rarely occurs in the maxillofacial region and skeletal system. Precise clinical and para-clinical investigation is necessary for the accurate diagnosis and correct treatment of this lesion. This paper presents a massive intravascular papillary endothelial hyperplasia lesion in the bony tissue of the mandible. Histopathology features, clinical appearance, and suitable management are discussed, with a complete review of the literature. The patient underwent composite resection of the lesion as well as reconstruction. No recurrence was observed during 6 years of follow-up. To the best of our knowledge, this is the fourth case of Masson's tumor in mandibular skeletal tissue, which has unique and distinctive features due to its size and location. A rare occurrence in skeletal tissue, complex clinical presentations, and complicated histopathologic findings present diagnostic challenges for treatment of this lesion.

Keyword

Intravascular papillary endothelial hyperplasia; Histopathology; Mandible; Bone

MeSH Terms

Diagnosis
Follow-Up Studies
Humans
Hyperplasia*
Mandible*
Recurrence

Figure

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  Fig. 1 Extraoral appearance of the lesion.

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  Fig. 2 Intraoral appearance of the lesion.

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  Fig. 3 Extraoral radiography of the lesion. A. Panoramic view. B. Posteroanterior mandible view.

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  Fig. 4 Computed tomography of the lesion. A. Three-dimensional view. B. Axial view.

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  Fig. 5 Resected specimen.

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  Fig. 6 Histologic section (H&E staining). A. Papillary endothelial cell proliferation in the dilated vascular lumen (×40). B. Papillae lined by plump endothelial cells (×100). C. Papillae with a vascular core lined by active endothelial cells (×200).

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