Korean J Med.  2019 Aug;94(4):330-342. 10.3904/kjm.2019.94.4.330.

Korean Heart Rhythm Society 2019 Practical Guidelines on Antithrombotic Therapy for AF Patients Undergoing Percutaneous Coronary Intervention or Structural Heart Disease Intervention

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, St. Vincent's Hospital, Catholic University of Korea, Suwon, Korea.
  • 2Division of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 3Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.
  • 4Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
  • 5Division of Cardiology, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
  • 6Division of Cardiology, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu, Korea.
  • 7Division of Cardiology, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul, Korea.
  • 8Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea. cby6908@yuhs.ac
  • 9Division of Cardiology, Department of Internal Medicine, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.

Abstract

The choice of an adequate antithrombotic regimen for atrial fibrillation patients undergoing emergent or elective percutaneous coronary intervention (PCI) should be based on the ischemic event and on the risk of bleeding. Recent randomized controlled trials have consistently demonstrated that dual antithrombotic therapeutic regimens, using non-vitamin K anticoagulants and clopidogrel, are superior to triple or dual therapy with warfarin and aspirin. This report incorporates findings of recent notable studies to provide concrete, clinically useful details and recommendations for bleeding risk assessment and optimal antithrombotic therapeutic strategies after PCI. In addition, we introduce guidelines for antithrombotic management after structural heart disease intervention.

Keyword

Atrial fibrillation; Anticoagulants; Guideline; Percutaneous coronary intervention

MeSH Terms

Anticoagulants
Aspirin
Atrial Fibrillation
Heart Diseases*
Heart*
Hemorrhage
Humans
Percutaneous Coronary Intervention*
Risk Assessment
Warfarin
Anticoagulants
Aspirin
Warfarin
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