Soonchunhyang Med Sci.  2019 Jun;25(1):65-68. 10.0000/sms.2019.25.1.65.

Two Cases of Radiologically Isolated Syndrome: First Case Report in Korea

• Im K
• Sunwoo JS
• Kwon KY
• Lee KB
• Ahn MY
• Roh H

• KMID: 2452799
• DOI: http://doi.org/10.0000/sms.2019.25.1.65

Abstract

With increasing sensitivity, availability, and use of magnetic resonance imaging (MRI) in the past three decades, there is also an increase in incidental abnormal findings. The most common findings of these incidental abnormalities are white matter lesions that are interpreted as demyelinating based on radiological criteria. MRI findings suggestive of multiple sclerosis (MS) in patients without typical MS symptoms and with normal neurologic findings are now defined as a radiologically isolated syndrome (RIS) which reported relatively low incidence, especially hard to find case report in Korea. The natural history and pathophysiologic processes of RIS remain largely unknown. The nature, prevalence, and long-term prognosis of RIS, as well as the role of disease-modifying therapy should be established in the future.

Keyword

Magnetic resonance imaging; Multiple sclerosis; Demyelinating diseases

MeSH Terms

Demyelinating Diseases
Humans
Incidence
Korea*
Magnetic Resonance Imaging
Multiple Sclerosis
Natural History
Neurologic Manifestations
Prevalence
Prognosis
White Matter