J Clin Neurol.  2019 Jul;15(3):398-400. 10.3988/jcn.2019.15.3.398.

Orbital Lymphoma Presenting with Inferior Rectus Palsy

• Jung JH
• Oh EH
• Shin DH
• Choi SY
• Choi KD
• Choi JH

• KMID: 2451127
• DOI: http://doi.org/10.3988/jcn.2019.15.3.398

Abstract

No abstract available.

MeSH Terms

Lymphoma*
Orbit*
Paralysis*

Figure

• 

  Fig. 1 Nine-gaze photograph shows the left eyelid swelling with mild chemosis, and depression deficit of the left eye in the left downward gaze (arrow, A), and the Hess test revealing the isolated IR palsy of the left eye (B). MRI scan of the orbit discloses a prominent enlargement of the left IR muscle (arrow, C), but also mild swelling of the left lacrimal gland, SR, and MR muscles. A section of the left IR muscle shows atypical lymphoid infiltrates with small dark nuclei and clear cytoplasm (hematoxylin & eosin; ×400, D). An FDG-PET scan reveals hypermetabolism in the left IR and pectoralis muscle (arrows, E). FDG: 18-fluoro-deoxyglucose, IO: inferior oblique, IR: inferior rectus, LR: lateral rectus, MR: medial rectus, SO: superior oblique, SR: superior rectus.

Reference

1. Choi KD, Choi JH, Choi HY, Huh YE, Kim HJ, Oh SY, et al. Inferior rectus palsy as an isolated ocular motor sign: acquired etiologies and outcome. J Neurol. 2013; 260:47–54.

2. Pusateri TJ, Sedwick LA, Margo CE. Isolated inferior rectus muscle palsy from a solitary metastasis to the oculomotor nucleus. Arch Ophthalmol. 1987; 105:675–677.

3. Chou TM, Demer JL. Isolated inferior rectus palsy caused by a metastasis to the oculomotor nucleus. Am J Ophthalmol. 1998; 126:737–740.

4. Eckardt AM, Lemound J, Rana M, Gellrich NC. Orbital lymphoma: diagnostic approach and treatment outcome. World J Surg Oncol. 2013; 11:73.

5. Demirci H, Shields CL, Karatza EC, Shields JA. Orbital lymphoproliferative tumors: analysis of clinical features and systemic involvement in 160 cases. Ophthalmology. 2008; 115:1626–1631.

6. Malik KJ, Berntson DG, Harrison AR. Lymphoplasmacytic lymphoma isolated to an extraocular muscle. Ophthalmic Plast Reconstr Surg. 2006; 22:400–401.

7. Izambart C, Robert PY, Petellat F, Petit B, Gastaud P, Lagier J, et al. Extraocular muscle involvement in marginal zone B-cell lymphomas of the orbit. Orbit. 2008; 27:345–349.

8. Benetatos L, Alymara V, Asproudis I, Bourantas KL. Rituximab as first line treatment for MALT lymphoma of extraocular muscles. Ann Hematol. 2006; 85:625–626.