Ann Lab Med.  2019 Sep;39(5):496-498. 10.3343/alm.2019.39.5.496.

Two Rare Cases of Therapy-Related Acute Lymphoblastic Leukemia in Patients With Plasma Cell Myeloma

Affiliations
  • 1Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. cjpark@amc.seoul.kr
  • 2Department of Internal Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Humans
Multiple Myeloma*
Plasma Cells*
Plasma*
Precursor Cell Lymphoblastic Leukemia-Lymphoma*

Figure

  • Fig. 1 Bone marrow aspirate findings at initial diagnosis of plasma cell myeloma (PCM) and the diagnosis of ALL in two patients. (A) Neoplastic plasma cells show medium size, round and eccentric nuclei, and blue cytoplasm at initial diagnosis of PCM in Case 1 (Wright stain, ×400). (B) Lymphoblasts show small to large size, fine chromatin pattern, one or two nucleoli, and moderate amount of cytoplasm and occasional cytoplasmic vacuoles at diagnosis of ALL in Case 1 (Wright stain, ×1,000). (C) Neoplastic plasma cells show medium size, round and eccentric nuclei, and blue cytoplasm at initial diagnosis of PCM in Case 2 (Wright stain, ×400). (D) Lymphoblasts show small to medium size, round nuclei and scanty cytoplasm at diagnosis of ALL in Case 2 (Wright stain, ×1,000).


Cited by  1 articles

Immune Checkpoint Programmed Cell Death Protein-1 (PD-1) Expression on Bone Marrow T Cell Subsets in Patients With Plasma Cell Myeloma
Min Young Lee, Chan-Jeoung Park, Young-Uk Cho, Eunkyoung You, Seongsoo Jang, Eul Ju Seo, Jung-Hee Lee, Dok Hyun Yoon, Cheolwon Suh
Ann Lab Med. 2021;41(3):259-267.    doi: 10.3343/alm.2021.41.3.259.


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