Endocrinol Metab.  2019 Jun;34(2):117-123. 10.3803/EnM.2019.34.2.117.

Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth

  • 1Department of Radiology, Withsim Clinic, Seongnam, Korea.
  • 2Department of Radiology and the Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. radbaek@naver.com


Thermal ablation (TA) procedures, such as radiofrequency ablation and laser ablation, are used for the treatment of benign thyroid nodules. Short-term studies (<2 years) have demonstrated that TA is an effective and safe procedure to improve cosmetic or symptomatic problems. However, studies including a longer follow-up period show that treated thyroid nodules can increase in size after 2 to 3 years. Several studies suggest that this results from regrowth at the undertreated nodule margins. Here, we review current data on regrowth after TA and describe factors related to it and possible approaches to prevent it.


Thyroid nodule; Ablation

MeSH Terms

Catheter Ablation
Follow-Up Studies
Laser Therapy
Thyroid Gland*
Thyroid Nodule*
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