Clin Pediatr Hematol Oncol.  2019 Apr;26(1):55-59. 10.15264/cpho.2019.26.1.55.

Various Complications after a Vascular Procedure in Patients with Hemophilia

Affiliations
  • 1Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, Korea. pysmd@khnmc.or.kr

Abstract

Hemophilia, an inherited bleeding disorder, is caused by a deficiency of coagulation factor VIII or IX. Most of patients with hemophilia need vascular procedure, which can lead to complications. Even though these complications can also occur in normal people, hemophilia and coagulopathy are particular risk factors. We reviewed medical records of patients with hemophilia who underwent vascular procedures and investigated its complications. Vessel-related complications occurred in five patients. Three patients had pseudoaneurysms after radial arterial puncture. All patients underwent coagulation factor replacement or ultrasound-guided compression and showed improvement. Neuropathy developed in one patient due to a hematoma that occurred after blood sampling. The hematoma improved, but motor and sensory deficits remained and neuropathy was confirmed. One patient died of uncontrolled bleeding after angiography. Vascular procedures require more attention in patients with hemophilia. Caution and prevention of complications is essential, even before the patient is diagnosed with hemophilia.

Keyword

Bleeding; Complication; Hemophilia; Procedure; Vascular

MeSH Terms

Aneurysm, False
Angiography
Blood Coagulation Factors
Factor VIII
Hematoma
Hemophilia A*
Hemorrhage
Humans
Medical Records
Punctures
Risk Factors
Blood Coagulation Factors
Factor VIII
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