J Vet Sci.  2019 May;20(3):e21. 10.4142/jvs.2019.20.e21.

Tidal volume in mechanically ventilated dogs: can human strategies be extrapolated to veterinary patients?

• Donati PA
• Plotnikow
• Benavides
• Belerenian G
• Jensen M
• Londoño L

• KMID: 2448705
• DOI: http://doi.org/10.4142/jvs.2019.20.e21

Abstract

This paper compares and describes the tidal volume (Vt) used in mechanically ventilated dogs under a range of clinical conditions. Twenty-eight dogs requiring mechanical ventilation (MV) were classified into 3 groups: healthy dogs mechanically ventilated during surgery (group I, n = 10), dogs requiring MV due to extra-pulmonary reasons (group II, n = 7), and dogs that required MV due to pulmonary pathologies (group III, n = 11). The median Vt used in each group was 16 mL/kg (interquartile range [IQR], 15.14-21) for group I, 12.59 mL/kg (IQR, 9-14.25) for group II, and 12.59 mL/kg (IQR, 10.15-14.96) for group III. The Vt used was significantly lower in group III than in group I (p = 0.016). The thoraco-pulmonary compliance was significantly higher in group I than in groups II and III (p = 0.011 and p = 0.006, respectively). The median driving pressure was similar among the groups with a median of 9, 11, and 10 cmH2O in groups I, II, and III, respectively (p = 0.260). Critically-ill dogs requiring MV due to the primary pulmonary pathology received a significantly lower Vt than healthy dogs but with a range of values that were markedly higher than those recommended by human guidelines.

Keyword

Ventilator-induced lung injury; mechanical ventilation; compliance; tidal volume

MeSH Terms

Animals
Compliance
Dogs*
Humans*
Pathology
Respiration, Artificial
Tidal Volume*
Ventilator-Induced Lung Injury