Int Neurourol J.  2019 Mar;23(1):69-74. 10.5213/inj.1836212.106.

Urodynamic and Bladder Diary Factors Predict Overactive Bladder-wet in Women: A Comparison With Overactive Bladder-dry

• Hsiao SM
• Wu PC
• Chang TC
• Chen CH
• Lin HH

• KMID: 2446748
• DOI: http://doi.org/10.5213/inj.1836212.106

Abstract

PURPOSE
To identify factors predicting the presence of overactive bladder syndrome (OAB)-wet, compared with OAB-dry.
METHODS
Between September 2007 and September 2013, the medical records of 623 women with OAB who completed a 3-day bladder diary and underwent urodynamic studies in a medical center were retrospectively reviewed. OAB-wet was diagnosed in patients who complained of at least one episode of urgency incontinence in the previous month; otherwise, OAB-dry was diagnosed. Multivariable logistic regression analysis was used to predict the presence of OAB-wet.
RESULTS
Age (odds ratio [OR], 1.05; P<0.001), maximal flow rate (Qmax) (OR,1.06; P<0.001), voided volume (OR, 0.996; P=0.001), detrusor pressure at maximal flow rate (PdetQmax) (OR, 1.02; P=0.003), urgency episodes (OR, 1.04; P<0.001) and urodynamic stress incontinence (OR,1.78; P=0.01) were independent predictors for the presence of OAB-wet vs. OAB-dry. If we use bladder contractility index as a variable for multivariable logistic regression analysis, bladder contractility index (OR, 1.012; P<0.001) become an independent predictor for OAB-wet.
CONCLUSIONS
A smaller bladder capacity and more frequent urgency episodes were predictors of OAB-wet, and the above findings indicate that OAB-wet and OAB-dry might be a continuum of OAB. Old age, high Qmax, high PdetQmax and urodynamic stress incontinence were also predictors for OAB-wet, and the above results reveal that OAB-wet and OAB-dry have partially different clinical and urodynamic features. Further studies might be performed to elucidate whether different treatment strategies between OAB-dry and OAB-wet can improve treatment efficacy.

Keyword

Overactiveurinary bladder; Urodynamics; Urgeurinary incontinence

MeSH Terms

Female
Humans
Logistic Models
Medical Records
Retrospective Studies
Treatment Outcome
Urinary Bladder*
Urinary Bladder, Overactive
Urodynamics*