Pediatr Gastroenterol Hepatol Nutr.  2019 May;22(3):262-269. 10.5223/pghn.2019.22.3.262.

Macronutrient Analysis of Human Milk according to Storage and Processing in Korean Mother

Affiliations
  • 1Department of Pediatrics, Chung-Ang University Hospital, Seoul, Korea. meltemp2@hanmail.net
  • 2Department of Pediatrics, College of Medicine, Chung-Ang University, Seoul, Korea.
  • 3Department of Pediatrics, Severance Children's Hospital, Seoul, Korea.

Abstract

PURPOSE
As the importance of breastfeeding has been reinforced, human milk is often stored for practical reasons. Therefore, we evaluated optimal storage and processing methods for human milk from a nutritional standpoint.
METHODS
Human milk samples were collected between June 2017 and February 2018. Also, data about maternal information were collected. Human milk was analyzed for macronutrients and caloric content. The samples were subdivided into groups for nutrient analysis. The control group (fresh milk) was not stored or processed. The other groups (9 groups) consisted of samples analyzed based on different storage temperatures (room temperature, refrigerated, frozen), defrosting methods (bottle warmer, room temperature thawing, microwave oven), and storage period (1 week, 1 month, 2 months) and compared with the control group.
RESULTS
There was no statistically significant difference in the nutrient content of human milk among the collected samples. A significant change in the content of macronutrients in milk samples was observed under storage condition at different temperatures for 1 week with subsequent thawing with bottle warmer compared to fresh milk. Under storage at −20°C for 1 week with subsequent thawing with different defrosting methods, a significant change in the content of macronutrients in milk samples was observed compared to fresh milk. After storage at −20°C for different periods and thawing with a bottle warmer, a significant change in macronutrient content in milk samples was observed compared to fresh milk regardless of the storage period.
CONCLUSION
Unlike previous guidelines, changes in macronutrient content in milk samples were observed regardless of the method of storing and thawing. Apparently, it is proposed that mothers should feed fresh human milk to their babies without storing.

Keyword

Human milk; Breastfeeding; Infant formula; Macronutrients

MeSH Terms

Breast Feeding
Humans*
Infant Formula
Methods
Microwaves
Milk
Milk, Human*
Mothers*

Reference

1. Van Rossum CT, Buchner FL, Hoekstra J. Quantification of health effects of breastfeeding: review of the literature and model simulation. Bilthoven: RIVM;2006.
2. ESPGHAN Committee on Nutrition. Agostoni C, Braegger C, Decsi T, Kolacek S, Koletzko B, et al. Breast-feeding: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2009; 49:112–125.
Article
3. Ip S, Chung M, Raman G, Chew P, Magula N, DeVine D, et al. Breastfeeding and maternal and infant health outcomes in developed countries. Evid Rep Technol Assess (Full Rep). 2007; 153:1–186.
4. Gartner LM, Morton J, Lawrence RA, Naylor AJ, O'Hare D, Schanler RJ, et al. Breastfeeding and the use of human milk. Pediatrics. 2005; 115:496–506.
Article
5. Horta BL, Victora CG. Long-term effects of breastfeeding: a systematic review. Geneva: World Health Organization;2013.
6. Riordan J, Wambach K. Breastfeeding and human lactation. 4th ed. Burlington (NJ): Jones & Bartlett Learning;2016.
7. Kramer MS, Kakuma R. Optimal duration of exclusive breastfeeding. Cochrane Database Syst Rev. 2012; CD003517.
Article
8. Academy of Breastfeeding Medicine Protocol Committee. Eglash A. ABM clinical protocol #8: human milk storage information for home use for full-term infants (original protocol March 2004; revision #1 March 2010). Breastfeed Med. 2010; 5:127–130.
Article
9. Schanler RJ. American Academy of Pediatrics. American College of Obstetricians and Gynecologists. Breastfeeding handbook for physicians. 2nd ed. Washington, D.C.: American Academy of Pediatrics;2014.
10. Kleinman RE. American Academy of Pediatrics Committee on Nutrition. Pediatric nutrition handbook. Elk Grove Village (IL): American Academy of Pediatrics;2009.
11. UNICEF. Breastfeeding, best start for your baby [Internet]. New York (NY): UNICEF;2018. cited 2018 Sep 30. Available from: https://www.unicef.org/pacificislands/Breastfeeding_BEST_START_FOR_YOU_BABY_web.pdf.
12. García-Lara NR, Vieco DE, De la Cruz-Bértolo J, Lora-Pablos D, Velasco NU, Pallás-Alonso CR. Effect of Holder pasteurization and frozen storage on macronutrients and energy content of breast milk. J Pediatr Gastroenterol Nutr. 2013; 57:377–382.
Article
13. Bertino E, Giribaldi M, Baro C, Giancotti V, Pazzi M, Peila C, et al. Effect of prolonged refrigeration on the lipid profile, lipase activity, and oxidative status of human milk. J Pediatr Gastroenterol Nutr. 2013; 56:390–396.
Article
14. Thatrimontrichai A, Janjindamai W, Puwanant M. Fat loss in thawed breast milk: comparison between refrigerator and warm water. Indian Pediatr. 2012; 49:877–880.
Article
15. Janjindamai W, Thatrimontrichai A, Maneenil G, Puwanant M. Soft plastic bag instead of hard plastic container for long-term storage of breast milk. Indian J Pediatr. 2013; 80:809–813.
Article
16. Ballard O, Morrow AL. Human milk composition: nutrients and bioactive factors. Pediatr Clin North Am. 2013; 60:49–74.
17. Mohd-Taufek N, Cartwright D, Davies M, Hewavitharana AK, Koorts P, McConachy H, et al. The effect of pasteurization on trace elements in donor breast milk. J Perinatol. 2016; 36:897–900.
Article
18. O'Connor DL, Ewaschuk JB, Unger S. Human milk pasteurization: benefits and risks. Curr Opin Clin Nutr Metab Care. 2015; 18:269–275.
19. Human Milk Banking Association of North America. Guidelines for the establishment and operation of a donor human milk bank. Fort Worth (TX): HMBANA;2015.
20. Peila C, Emmerik NE, Giribaldi M, Stahl B, Ruitenberg JE, van Elburg RM, et al. Human milk processing: a systematic review of innovative techniques to ensure the safety and quality of donor milk. J Pediatr Gastroenterol Nutr. 2017; 64:353–361.
Article
21. Brändén CI, Tooze J. Introduction to protein structure. New York (NY): Garland Pub.;2009.
22. Bransburg-Zabary S, Virozub A, Mimouni FB. Human milk warming temperatures using a simulation of currently available storage and warming methods. PLoS One. 2015; 10:e0128806.
Article
23. Bohr H, Bohr J. Microwave-enhanced folding and denaturation of globular proteins. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 2000; 61:4310–4314.
Article
24. Kim YJ. Important role of medical training curriculum to promote the rate of human milk feeding. Pediatr Gastroenterol Hepatol Nutr. 2017; 20:147–152.
Article
Full Text Links
  • PGHN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr