Korean J Gastroenterol.  2019 Apr;73(4):235-238. 10.4166/kjg.2019.73.4.235.

Mucinous Non-neoplastic Cyst of the Pancreas

Affiliations
  • 1Department of Surgery, Wonkwang University School of Medicine, Iksan, Korea. knife@wonkwang.ac.kr
  • 2Department of Pathology, Wonkwang University School of Medicine, Iksan, Korea.

Abstract

Cystic neoplasms of the pancreas consist of a wide range of pathological entities and are being detected more frequently due to advances in cross-sectional imaging modalities and increasing numbers of periodic health checkups. The majority of pancreatic cystic neoplasms are intraductal papillary mucinous neoplasms, serous neoplasms, and mucinous cystic neoplasms, but recently, rare cases of mucinous non-neoplastic cyst of the pancreas (MNCP) have been reported, and despite the availabilities of modern imaging systems, such as MRI and CT, the differentiation of non-neoplastic and neoplastic cysts remains challenging. Herein, we report our experience of a 65-year-old male case with an MNCP.

Keyword

Pancreatic cyst; Mucins; Pancreatic neoplasms

MeSH Terms

Aged
Humans
Magnetic Resonance Imaging
Male
Mucins*
Pancreas*
Pancreatic Cyst
Pancreatic Neoplasms
Mucins

Figure

  • Fig. 1 Upper gastrointestinal endoscopy revealed an external compressive lesion at the posterior wall of the stomach midbody.

  • Fig. 2 (A) Abdominal computed tomography image showing a 2.5 cm, round, hypoattenuated cystic lesion without any enhanced solid portion in the pancreatic body. (B) Three-dimensional magnetic resonance cholangiopancreatogram showing a 2.5 cm, cystic mass without any solid portion in the pancreatic body surrounded by multiple, small daughter cysts. (C) Endoscopic ultrasound revealed a non-septated, 2.5 cm, single cyst with mural nodularity. Circles and an arrow indicated a cystic lesion.

  • Fig. 3 (A) Cut surface of the resected specimen showing the unilocular cyst. (B) H&E-stained section shows the cyst lined with mucinous epithelial cells (arrow), a fibrous stroma (arrowhead) and adjacent normal pancreas (asterisk) (H&E, ×100).


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