Dement Neurocogn Disord.  2015 Mar;14(1):24-30. 10.12779/dnd.2015.14.1.24.

The Relationship between Geriatric Depression Scale Structure and Cognitive-Behavioral Aspects in Patients with Alzheimer's Disease

Affiliations
  • 1Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea. kwakdr@gmail.com
  • 2Department of Psychiatry, Yong-in Mental Hospital, Yongin, Korea.
  • 3Department of Neurology, VHS Medical Center, Seoul, Korea.

Abstract

BACKGROUND AND PURPOSE
Although the 15-item Geriatric Depression Scale (GDS15) is a widely used depression screening questionnaire, the implications of the GDS15 in patients with Alzheimer's disease (AD) are questionable. We designed this study to explore the GDS15 factor structure and the relationships between these factors and cognitive-behavioral aspects.
METHODS
The GDS15, cognitive function tests, and the Korean-Neuropsychiatry Inventory were administered to 310 patients with probable AD, who were not medicated before visiting the hospital. Three factors were identified by principal components analysis. A bivariate correlation analysis was conducted to determine the relationships between factors and neurocognitive and behavior symptoms.
RESULTS
Factor 2 was correlated with the Korean Boston Naming Test, calculating ability, the go-no-go test, the Controlled Oral Word Association Test (COWAT), the Color Word Stroop Test (CWST; words and color), aggression, depression, and apathy. Factor 3 was correlated with calculating ability, the Seoul Verbal Learning Test, immediate recall, copy, and delayed recall on the Rey-Osterieth Complex Figure Test, contrasting on the COWAT, and words and delusion on the CWST. We identified three factors and revealed that the GDS15 may be comprised of a heterogeneous scale.
CONCLUSIONS
These results suggest that the GDS15 may be comprised of a heterogeneous scale and suggest multi-dimensional properties of the GDS15 in patients with AD.

Keyword

15-item Geriatric Depression Scale; Alzheimer's disease; Neuropsychiatry Inventory; factor analysis; cognitive function

MeSH Terms

Aggression
Alzheimer Disease*
Apathy
Delusions
Depression*
Factor Analysis, Statistical
Humans
Mass Screening
Memory, Short-Term
Seoul
Stroop Test
Verbal Learning
Word Association Tests
Surveys and Questionnaires
Full Text Links
  • DND
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error