Dement Neurocogn Disord.  2015 Jun;14(2):94-97. 10.12779/dnd.2015.14.2.94.

Splenial Corpus Callosum Infarction Presenting with Unilateral Prosopometamorphopsia: A Case Report

• Lee CM

• KMID: 2443008
• DOI: http://doi.org/10.12779/dnd.2015.14.2.94

Abstract

BACKGROUND
Prosopometamorphopsia is a disorder of face perception in which faces appear distorted to the perceiver. Cases with unilateral prosopometamorphopsia caused by splenial lesion have been very rarely reported.
CASE REPORT
A 52-year-old right-handed woman complained that the left half of people's faces looked distorted. She stated that objects other than the face looked normal. Brain magnetic resonance imaging revealed an infarction of the left splenium of the corpus callosum. Electroencephalography and automated perimetry were normal.
CONCLUSIONS
The mechanism of unilateral prosopometamorphopsia remains unclear. However, it could be a dominant hemisphere-specific disconnection sign.

Keyword

prosopometamorphopsia; splenium; disconnection sign

MeSH Terms

Brain
Corpus Callosum*
Electroencephalography
Female
Humans
Infarction*
Magnetic Resonance Imaging
Middle Aged
Visual Field Tests

Figure

• 

  Fig. 1 Illustration and drawing of facial distortions. A: The illustration was modified according to the patient's statement. B: The figure was drawn by the patient 1 year after onset.

• 

  Fig. 2 Axial brain MR images of the patient. A: Diffusion-weighted image demonstrates a high signal intensity lesion in the left splenium. B: T2-weighted image obtained 1 month after onset shows a tissue loss in the left splenial lesion. C: Follow-up T2-weighted image 1 year later shows an atrophic change of the left splenial lesion.

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