J Korean Neurol Assoc.
1997 Apr;15(2):394-398.
Cerebral vasospasm in eclampsia: Report of a case
- Affiliations
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- 1Department of Neurology, Seoul National University Hospital, Korea.
- 2Department of Neurology, Seoul City Boramae Hospital, Korea.
Abstract
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BACKGROUND AND SIGNIFICANCE: Eclampsia is defined by the concurrence of proteinuria, hypertension, convulsion and/or coma in the intrapartum or immediate postpartum period. Vasospasm of cerebral arteries is thought to be the basic pathophysiology of eciampsia. However there has yet been little direct evidence for vasospasm of cerebral arteries. Case : A 22-year old pregnant woman was admitted because of a labor pain and headache at the 40th week of gestation. She had no history of hypertension, seizure and migraine. On admission, hypertension and proteinuria were detected. She experienced a generalized tonic-clonic seizure and became comatose. Subarachnoid and intracranial hemorrage was excluded by cranial CT and lumbar puncture. Magnetic resonance angiography (MRA) on the 8th day after admission revealed diffuse vasospasm of cerebral arteries. Vasospasm disappeared on follow-up MRA performed 6 weeks later.
CONCLUSION
Cerebral vasospasm was confirmed by MRA. In Korea, this is the first demonstration of reversible cerebral vasospasm in eclampsia.