J Korean Soc Radiol.  2019 Mar;80(2):359-364. 10.3348/jksr.2019.80.2.359.

Intrahepatic Splenosis Mimicking Hepatocellular Carcinoma: A Case Report

Affiliations
  • 1Department of Radiology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea. msj542@hallym.or.kr

Abstract

Splenosis refers to autotransplantation of splenic tissue into intraabdominal, intrathoracic or even any other parts of body and occurs after splenic trauma or splenectomy. Hepatic splenosis is usually incidental found during imaging workup. It can mimic other hypervascular mass because it presents vivid and heterogeneous enhancement representing that of splenic tissue. So far, about 20 cases of intrahepatic splenosis have been described in the literature. Herein we report a case of intrahepatic splenosis mimicking hepatocellular carcinoma in a patient with liver cirrhosis. The patient was finally diagnosed on the basis of specific radionuclide imaging.


MeSH Terms

Autografts
Carcinoma, Hepatocellular*
Humans
Liver Cirrhosis
Radionuclide Imaging
Splenectomy
Splenosis*
Transplantation, Autologous

Reference

1. Wang WC, Li XF, Yan ZL, Wang Y, Ma JY, Shi LH, et al. Intrahepatic splenosis mimics hepatocellular carcinoma in a patient with chronic hepatitis B: a case report and literature review. Medicine (Baltimore). 2017; 96:e8680.
2. Choi GH, Ju MK, Kim JY, Kang CM, Kim KS, Choi JS, et al. Hepatic splenosis preoperatively diagnosed as hepatocellular carcinoma in a patient with chronic hepatitis B: a case report. J Korean Med Sci. 2008; 23:336–341.
Article
3. Chung WJ. Splenosis mimicking hepatocellular carcinoma. Korean J Gastroenterol. 2014; 64:173–175.
Article
4. Liu C, Liu J, Wang F. Intrahepatic splenosis mimicking liver cancer: report of a case and review of literature. Int J Clin Exp Pathol. 2015; 8:1031–1035.
5. Sato N, Abe T, Suzuki N, Waragai M, Teranishi Y, Takano Y, et al. Intrahepatic splenosis in a chronic hepatitis C patient with no history of splenic trauma mimicking hepatocellular carcinoma. Am J Case Rep. 2014; 15:416–420.
Article
6. Pekkafali Z, Karsli AF, Silit E, Bas¸ekim CC, Narin Y, Mutlu H, et al. Intrahepatic splenosis: a case report. Eur Radiol. 2002; 12:Suppl 3. S62–S65.
Article
7. Li T, Yang XY, Tang ZY. Intrahepatic and intraperitoneal splenosis mimicking hepatocellular carcinoma with abdominal wall metastasis in a patient with hepatitis C cirrhotic liver. Surgery. 2015; 157:954–956.
Article
Full Text Links
  • JKSR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2025 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr