Clin Psychopharmacol Neurosci.  2019 Feb;17(1):130-133. 10.9758/cpn.2019.17.1.130.

Recurrent Psychosis after Phentermine Administration in a Young Female: A Case Report

Affiliations
  • 1Department of Psychiatry, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. jjean@catholic.ac.kr
  • 2International Health Care Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Phentermine is a sympathomimetic amine, like amphetamine, which is one of the most often prescribed drugs for weight loss. Although exact mechanism of phentermine causing psychosis is still not clear, numerous reports already showed that phentermine can induce psychosis. Psychotic symptoms are generally resolved once the medications are stopped. In contrast, we present a case of a 25-years-old Asian female patient who developed psychotic symptoms repeatedly after phentermine administrations. This case suggests that phentermine can cause psychotic episodes repeatedly, resulting in chronic occupational and social impairment. Therefore, a precautious measure such as government regulations for physicians prescribing and an education for patients taking phentermine are urgently needed.

Keyword

Phentermine; Adverse reaction; Psychotic disorders; Recurrence

MeSH Terms

Amphetamine
Asian Continental Ancestry Group
Education
Female*
Government Regulation
Humans
Phentermine*
Psychotic Disorders*
Recurrence
Weight Loss
Amphetamine
Phentermine
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