Korean J Pediatr Infect Dis.  1997 Nov;4(2):303-307. 10.14776/kjpid.1997.4.2.303.

Two Cases of Hand-Foot-Mouth Disease with Neurologic Manifestations

Affiliations
  • 1Department of Pediatrics, Catholic University Medical College, Seoul, Korea.

Abstract

Hand-Foot-Mouth disease, which has a various enanthem-exanthem complex at the tongue, buccal mucosa, hands and feats and buttock area with febrile illness, is usually caused by Coxscakie virus type A(16). Generally, this disease shows self limited course and good prognosis without neurologic manifestations. However, enterovirus 71, which was newly discovered and reported in 1974, can cause the striking features of Hand-Foot-Mouth disease outbreaks and has neuropathogenic potentials of polio-like paralytic illness including aseptic meningitis, meningoencephalitis and respiratory disease. We experienced a case of Hand-Foot-Mouth disease with polyradiculitis manifestations, and a case of Hand-Foot-Mouth disease with meningoencephalitis. Therfore, we report these cases with brief review of related literatures.

Keyword

Hand-Foot-Mouth disease; Polyradiculitis; Meningoencephalitis

MeSH Terms

Buttocks
Disease Outbreaks
Enterovirus
Hand
Meningitis, Aseptic
Meningoencephalitis
Mouth Mucosa
Neurologic Manifestations*
Polyradiculopathy
Prognosis
Strikes, Employee
Tongue
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