Ann Dermatol.  2019 Apr;31(2):238-240. 10.5021/ad.2019.31.2.238.

Diffuse Normolipemic Plane Xanthomatosis with Immunoglobulin-Lambda Light-Chain Deposition in a Patient with Multiple Myeloma

• Lee SH
• Shin JY
• Lee SH
• Park YL

• KMID: 2439077
• DOI: http://doi.org/10.5021/ad.2019.31.2.238

Abstract

No abstract available.

MeSH Terms

Humans
Multiple Myeloma*
Xanthomatosis*

Figure

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  Fig. 1 (A) Symmetrically distributed yellow plaques on both periorbital areas. (B) Yellow patches, papules on the axilla. We received the patient's consent form about publishing all photographic materials.

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  Fig. 2 (A) Scattered foamy histiocytes are observed in the upper and mid dermis, with an admixture of histiocytes and lymphocytes (H&E, ×200). (B) Immunohistochemical staining was diffusely positive for CD68 (CD68, ×100). (C) Dense staining throughout the entire dermis for the immunoglobulin-lambda light chain is noted (lambda chain, ×100). (D) Globular deposits of homogenous, faintly eosinophilic materials in the papillary dermis (H&E, ×200).

Reference

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