Ann Lab Med.  2019 Jul;39(4):400-402. 10.3343/alm.2019.39.4.400.

First Case of Cellular Cannibalism in Small-Cell Carcinoma of the Bladder Detected in Peripheral Blood

• Kang H
• Kim DH
• Lee W
• Ha J
• Ryoo N
• Jeon DS
• Jung HR

• KMID: 2438888
• DOI: http://doi.org/10.3343/alm.2019.39.4.400

Abstract

No abstract available.

MeSH Terms

Cannibalism*
Urinary Bladder*

Figure

• 

  Fig. 1 Cellular cannibalism on peripheral blood (PB) smear and bone marrow (BM) biopsy section. (A, B) PB smear showing a tumor cell with a crescentic nucleus engulfing another cell and a large tumor cell enclosing a smaller one in its cytoplasm. (C) PB smear showing “molding” of adjacent cells (black arrows; ×1,000, Wright-Giemsa). (D) BM biopsy section showing cannibalistic cells (yellow arrows; ×400, hematoxylin & eosin).

Reference

1. Gupta N, Jadhav K, Shah V. Emperipolesis, entosis, and cell cannibalism: demystifying the cloud. J Oral Maxillofac Pathol. 2017; 21:92–98. PMID: 28479694.

2. Steinhaus J. Ueber carcinoma-einschlüsse. Virchows Arch Pathol Anat. 1891; 126:533–541.

3. Bauchwitz MA. The bird's eye cell: cannibalism or abnormal division of tumor cells. Acta Cytol. 1981; 25:92.

4. Towers KH, Melamed MR. Absence of prognostic features in the cytology of effusions due to mammary cancer. Acta Cytol. 1979; 23:30–34. PMID: 285549.

5. Craig ID, Desrosiers P, Lefcoe MS. Giant-cell carcinoma of the lung. A cytologic study. Acta Cytol. 1983; 27:293–298. PMID: 6575547.

6. Sarode GS, Sarode SC, Karmarkar S. Complex cannibalism: an unusual finding in oral squamous cell carcinoma. Oral Oncol. 2012; 48:e4–e6. PMID: 21940197.

7. Bansal C, Tiwari V, Singh US, Srivastava AN, Misra JS. Cell cannibalism: acytological study in effusion samples. J Cytol. 2011; 28:57–60. PMID: 21713148.

8. Koss LG, Melamed MR. Koss' diagnostic cytology and its histopathologic bases. Vol. 1. 5th ed. Philadelphia: Lippincott Williams and Wilkins;2007. p. 656–657.

9. Ismaili N. A rare bladder cancer-small cell carcinoma: review and update. Orphanet J Rare Dis. 2011; 6:75. PMID: 22078012.

10. Sarode SC, Sarode GS. Cellular cannibalism in central and peripheral giant cell granuloma of the oral cavity and predict biological behavior of the lesion. J Oral Pathol Med. 2014; 43:459–463. PMID: 24112367.