Korean J Med.  2019 Feb;94(1):40-56. 10.3904/kjm.2019.94.1.40.

The 2018 Korean Heart Rhythm Society Practical Guidelines on the use of Non-Vitamin K-Antagonist Oral Anticoagulants: Bleeding Control and Perioperative Management

Affiliations
  • 1Department of Cardiology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 2Division of Cardiology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea. hongeuy1046@gmail.com
  • 3Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
  • 4Department of Cardiology, Busan National University College of Medicine, Busan, Korea.
  • 5Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
  • 6Department of Cardiology, Ewha Womans University Medical Center, Seoul, Korea.
  • 7Department of Cardiology, Chonnam National University Hospital, Chonnam National University College of Medicine, Gwangju, Korea.
  • 8Department of Cardiology, Hanyang University Guri Hospital, Guri, Korea.
  • 9Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Although non-vitamin K-antagonist oral anticoagulants (NOACs) reduce major bleeding events in patients with atrial fibrillation more effectively than does warfarin, a significant bleeding risk remains. Patients exhibiting current bleeding and those who are expected to bleed require appropriate management, because NOAC discontinuation may increase the thromboembolic risk. This article details general management principles for patients experiencing current bleeding and those undergoing invasive surgery while on NOACs.

Keyword

Atrial fibrillation; Anticoagulants; Guideline; Perioperative care; Hemorrhage

MeSH Terms

Anticoagulants*
Atrial Fibrillation
Heart*
Hemorrhage*
Humans
Perioperative Care
Warfarin
Anticoagulants
Warfarin
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