Cancer Res Treat.  2019 Jan;51(1):289-299. 10.4143/crt.2018.053.

Health-Related Quality of Life, Perceived Social Support, and Depression in Disease-Free Survivors Who Underwent Curative Surgery Only for Prostate, Kidney and Bladder Cancer: Comparison among Survivors and with the General Population

• Shin DW
• Park HS
• Lee SH
• Jeon SH
• Cho S
• Kang SH
• Park SC
• Park JH
• Park J

• KMID: 2437620
• DOI: http://doi.org/10.4143/crt.2018.053

Abstract

PURPOSE
The purpose of this study was to compare health-related quality of life (HRQoL) of disease-free prostate (PC), kidney (KC), and bladder cancer (BC) survivors with that of the general population.
MATERIALS AND METHODS
Our study included 331 urological cancer (UC) survivors (114 PC, 108 KC, and 109 BC) aged ≥ 50 years disease-free for at least 1 year after surgery. The control group included 1,177 subjects without a history of cancer. The HRQoL was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30, the Duke-UNC Functional Social Support Questionnaire, and the Patient Health Questionnaire-9.
RESULTS
There was no significant difference between the groups in terms of any of the functioning sub-scales and symptoms, except significantly lower social functioning observed in BC survivors than that observed in KC survivors. Although the three groups of UC survivors showed essentially similar functioning sub-scales and symptoms when compared to the general population, PC and BC survivors showed significantly lower social functioning and a lower appetite than that observed in controls. KC survivors showed lower physical functioning, as well as higher pain and dyspnea. Although all three groups of UC survivors reported higher financial difficulties, they also reported higher perceived social support than that reported by the non-cancer control group. No statistically significant difference was observed in terms of depressive symptoms between each group of UC survivors and the general population.
CONCLUSION
Disease-free survivors of the three major types of UCs showed generally similar HRQoL compared to the general population, as well as compared to each other.

Keyword

Health-related quality of life; Depression; Cancer survivors; Urological neoplasm; Prostatic neoplasms; Kidney neoplasms; Urinary bladder neoplasms

MeSH Terms

Appetite
Depression*
Dyspnea
Humans
Kidney Neoplasms
Kidney*
Prostate*
Prostatic Neoplasms
Quality of Life*
Survivors*
Urinary Bladder Neoplasms*
Urinary Bladder*
Urologic Neoplasms

Figure

• 

  Fig. 1. Comparison of health-related quality of life, functional social support, and depression between non-cancer control and survivors of three major types of urological cancer by time elapsed from the cancer treatment. *p < 0.05 as compared to control.

Reference

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