Korean J Psychosom Med.  2018 Dec;26(2):164-171. 10.22722/KJPM.2018.26.2.164.

The Relationship between Suicide Attempts and Serum Lipids in Patients Admitted with Depression

• Park SH
• Kim SJ
• Kim JW
• Oh HS
• Lee SM
• Jun JY
• Im WY

• KMID: 2437568
• DOI: http://doi.org/10.22722/KJPM.2018.26.2.164

Abstract

OBJECTIVES
Depression is a common mental illness and a major cause of suicide. Although serum lipids have been associated with depression and suicide, there has been much debate. In this study, we investigated the relationship between depression, suicide, and serum lipids in patients admitted with depressed mood.
METHODS
A total of 134 subjects were divided into 86 non-suicide patients and 48 suicide attempters. The serum lipid levels and sub-scores of the Korean Symptom Checklist-95 (KSCL95) were compared. We also investigated the relationship between serum lipids and sub-scores of KSCL95 and investigated whether serum lipids were risk factors for suicide attempts.
RESULTS
There was no difference in serum lipids between the two groups. Among the sub-items of KSCL95, obsession was higher in non-suicide group. Triglyceride showed positive correlations with anxiety, phobic anxiety, agoraphobia, schizophrenia, and self-regulation problem. High triglyceride was a risk factor for suicide attempts.
CONCLUSIONS
Triglyceride is associated with depression, anxiety, and self - regulation, and high serum triglyceride levels may be a risk factor for suicide attempts.

Keyword

Depression; Suicide; Self-mutilating behavior; Suicide-related behavior; Serum lipid; Triglyceride; Cholesterol

MeSH Terms

Agoraphobia
Anxiety
Cholesterol
Depression*
Humans
Obsessive Behavior
Risk Factors
Schizophrenia
Self-Control
Suicide*
Triglycerides
Cholesterol