J Korean Neurol Assoc.
2018 May;36(2):100-102. 10.17340/jkna.2018.2.8.
Miller-Fisher Syndrome Presenting with Bilateral Pseudo-Internuclear Ophthalmoplegia
- Affiliations
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- 1Department of Neurology, Kyung Hee University Hospital, Seoul, Korea. medicj80@hanmail.net
- 2Department of Neurology, Kyung Hee University Hospital at Kangdong, Seoul, Korea.
- 3Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- KMID: 2436107
- DOI: http://doi.org/10.17340/jkna.2018.2.8
Abstract
- Bilateral internuclear ophthalmoplegia (INO) refers to a specific gaze abnormality of bilateral adduction deficits, often accompanied by dissociated abducting nystagmus, caused by medial longitudinal fasciculus lesions usually due to multiple sclerosis or stroke. We report a 63-year-old man with clinical features of Miller-Fisher syndrome (MFS), consisting of ataxia, areflexia, and external ophthalmoplegia which mimicked bilateral-INO without an identifiable central lesion. Although bilateral adduction deficits are usually caused by central lesions, peripheral nervous damage by MFS is needed to be considered.
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