J Korean Neurol Assoc.  2018 Nov;36(4):358-362. 10.17340/jkna.2018.4.18.

Delayed Anoxic Encephalopathy after Carbon Monoxide Poisoning: Evaluation of Therapeutic Effect by Serial Diffusion-Tensor Magnetic Resonance Imaging and Neurocognitive Test

• Ryu HS
• Kim Y
• Jung BK
• Kim YW

• KMID: 2435852
• DOI: http://doi.org/10.17340/jkna.2018.4.18

Abstract

Delayed anoxic encephalopathy after carbon monoxide (CO) poisoning is characterized by neurological deterioration that occurs after recovery from acute CO intoxication. There has been no established therapy. We report a patient recovered from acute CO intoxication developed various neurological symptoms. After the administration of high dose prednisolone and anticholinesterase inhibitor, the therapeutic effect was remarkable and confirmed by quantitative analysis of diffusion-tensor imaging (DTI). DTI could be used to evaluate the therapeutic effect for delayed anoxic encephalopathy after CO poisoning.

Keyword

Carbon monoxide; Leukoencephalopathies; Diffusion tensor imaging

MeSH Terms

Carbon Monoxide Poisoning*
Carbon Monoxide*
Carbon*
Diffusion Tensor Imaging
Humans
Hypoxia, Brain*
Leukoencephalopathies
Magnetic Resonance Imaging*
Poisoning
Prednisolone
Carbon
Carbon Monoxide
Prednisolone