Korean J Blood Transfus.
2018 Aug;29(2):188-193. 10.17945/kjbt.2018.29.2.188.
A Case of Sickle Cell Anemia with a Lack of High Frequency Red Blood Cell Antigen
- Affiliations
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- 1Department of Laboratory Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.
- 2Department of Laboratory Medicine, Pusan National University Hospital, Busan, Korea. hhkim@pusan.ac.kr
- 3Department of Laboratory Medicine, Kosin University College of Medicine, Busan, Korea.
- 4Department of Pediatrics, Kosin University College of Medicine, Busan, Korea.
- KMID: 2435677
- DOI: http://doi.org/10.17945/kjbt.2018.29.2.188
Abstract
- Patients with sickle cell anemia are chronically transfused. Therefore, it is important to prevent the alloimmunization of RBC antigens. The authors identified a high frequency antigen-negative blood group in patients with sickle cell anemia. As the number of foreigners residing in Korea is increasing, it is necessary to know what to consider when transfusing blood to sickle cell anemia patients. Patients with sickle cell anemia should be informed of the exact blood group type using extended RBC typing to confirm the ABO, Rh, Kell, and Duffy blood types at diagnosis or before the first blood transfusion. Extended matched blood transfusion can reduce the risk of alloimmunization of RBC antigens.
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