Korean J Med.
2018 Aug;93(4):369-378. 10.3904/kjm.2018.93.4.369.
Predictors of One-Year Mortality in Smokers with Acute Myocardial Infarction
- Affiliations
-
- 1The Heart Center, Chonnam National University Hospital, Gwangju, Korea. myungho@chollian.net
- 2The Heart Research Center Designated by Korea Ministry of Health and Welfare, Gwangju, Korea.
- 3Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Korea.
- 4Department of Cardiology, Chungbuk National University Hospital, Cheongju, Korea.
- 5Department of Cardiology, Kyunghee University Hospital, Seoul, Korea.
- 6Department of Cardiology, Yeungnam University Hospital, Daegu, Korea.
- KMID: 2435074
- DOI: http://doi.org/10.3904/kjm.2018.93.4.369
Abstract
- BACKGROUND/AIMS
It is well known that smoking is associated with clinical outcomes in patients with acute myocardial infarction (AMI). In this study, we aimed to predict the one-year mortality in AMI patients that smoked.
METHODS
Of the AMI patients who were enrolled in the Korean Acute Myocardial Infarction Registry-National Institutes of Health study, 5,110 were current smokers (57.1 ± 11.6 years, male 95%), and these patients were included in the present study. Patients were divided into two groups; group I (survival group, n = 4,844, 56.5 ± 11.3 years, male 95%) and group II (deceased group, n = 266, male 88%). Clinical characteristics, coronary angiographic findings, procedural characteristics, and independent factors related to one-year mortality were analyzed.
RESULTS
In group II, the incidence of hypertension and diabetes were significantly higher than in group I, and the patients were significantly older. Patients with history of angina pectoris, myocardial infarction, and heart failure were significantly more common in group II than in group I. Smoking duration and pack-years of smoking were also significantly longer in group II than in group I. Multivariate analysis revealed that creatine > 2 mg/dL, left ventricular ejection fraction < 40%, Killip class ≥ II, age ≥ 65 years, and post-percutaneous coronary intervention thrombolysis in myocardial infarction (post-PCI TIMI) flow ≤ II were independent factors of mortality during the one-year follow-up.
CONCLUSIONS
The predictors of one-year mortality in AMI patients with smoking were renal and left ventricular dysfunction, high Killip class, old age, and low post-PCI TIMI flow.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The One-Year Prognostic Value of the Pre-Discharge ECG after the First Acute Myocardial Infarction
- Three Cases of Ventricular Septal Rupture after Acute Myocardial Infarction
- Invasive Treatment of Acute Myocardial Infarction: What is the Optimal Therapy for Acute Myocardial Infarction?
- Two-Dimensional Echocardiographic Predictors of Ventricular Enlargement after Acute Myocardial Infarction
- Clinical Study on Acute Myocardial Infarction
