J Neurocrit Care.  2018 Dec;11(2):143-147. 10.18700/jnc.180063.

Cardiac Arrest in Conjunction with Hypoglycemia in a Non-Diabetic Patient with Cerebral Infarction

Affiliations
  • 1Department of Neurology, Yonsei University Wonju College of Medicine, Wonju, Korea. bstuff@yonsei.ac.kr

Abstract

BACKGROUND
Hypoglycemia is uncommon in people without diabetes. There have been only a few reports of cardiac arrest in conjunction with hypoglycemia in non-diabetic patients.
CASE REPORT
A 66-year-old man visited the emergency room with dizziness. He was a chronic alcoholic. Laboratory test showed no evidence of diabetes mellitus. Brain magnetic resonance imaging revealed a left cerebellar infarction. Abdomen computed tomography demonstrated liver cirrhosis with minimal ascites. During his hospital stay, he consumed only a small amount of food because of nausea and headache. On hospital day 4, he had a cardiac arrest after two seizure episodes. His blood glucose was 10 mg/dL. The combination of liver cirrhosis, renal failure and poor oral intake was presumed to be the causes of the severe hypoglycemia.
CONCLUSION
We report a rare case of cardiac arrest occurring in conjunction with severe hypoglycemia in a non-diabetic patient with cerebral infarction.

Keyword

Hypoglycemia; Heart arrest; Cerebral infarction

MeSH Terms

Abdomen
Aged
Alcoholics
Ascites
Blood Glucose
Brain
Cerebral Infarction*
Diabetes Mellitus
Dizziness
Emergency Service, Hospital
Headache
Heart Arrest*
Humans
Hypoglycemia*
Infarction
Length of Stay
Liver Cirrhosis
Magnetic Resonance Imaging
Nausea
Renal Insufficiency
Seizures
Blood Glucose

Figure

  • Figure 1. Computed tomography demonstrating liver cirrhosis with minimal ascites

  • Figure 2. (A) Initial brain computed tomography (CT) image showing left cerebellar low density. (B) Brain magnetic resonance image of acute left cerebellar infarction with compression of brainstem. (C) Brain CT image after the first cardiac arrest showing left cerebellar low density with mild brainstem compression.


Reference

1. Service FJ. Hypoglycemic disorders. N Engl J Me. 1995; 332:1144–52.
Article
2. Shimizu K, Ogura H, Wasa M, Hirose T, Shimazu T, Nagasaka H, et al. Refractory hypoglycemia and subsequent cardiogenic shock in starvation and refeeding: report of three cases. Nutrition. 2014; 30:1090–2.
Article
3. Luu M, Stevenson WG, Stevenson LW, Baron K, Walden J. Diverse mechanisms of unexpected cardiac arrest in advanced heart failure. Circulation. 1989; 80:1675–80.
Article
4. Çöllüoğlu İT, Dursun H, Yılmaz M, Ergene AO. Hypoglycemia detected during cardiac arrest of a non-diabetic patient with heart failure. Turk Kardiyol Dern Ars. 2015; 43:196–8.
5. American Diabetes Association. Standards of medical care in diabetes--2014. Diabetes Care. 2014; 37 Suppl 1:S14–80.
6. Korean Diabetes Association Education Committee. The guide for diabetes education. 3rd ed. Seoul: Gold’ Planning and Development;2013. p. 134–159. 134-9, 151-9.
7. Moheet A, Seaquist ER. Hypoglycemia as a driver of cardiovascular risk in diabetes. Curr Atheroscler Rep. 2013; 15:351.
Article
8. Reno CM, Daphna-Iken D, Chen YS, VanderWeele J, Jethi K, Fisher SJ. Severe hypoglycemia-induced lethal cardiac arrhythmias are mediated by sympathoadrenal activation. Diabetes. 2013; 62:3570–81.
Article
9. Beleza P. Acute symptomatic seizures: a clinically oriented review. Neurologist. 2012; 18:109–19.
10. Bilhimer MH, Treu CN, Acquisto NM. Current practice of hypoglycemia management in the ED. Am J Emerg Med. 2017; 35:87–91.
Article
11. Pasala S, Dendy JA, Chockalingam V, Meadows RY. An inpatient hypoglycemia committee: development, successful implementation, and impact on patient safety. Ochsner J. 2013; 13:407–12.
12. Mellinkoff SM, Tumulty PA. Hepatic hypoglycemia; its occurrence in congestive heart failure. N Engl J Med. 1952; 247:745–50.
13. Kim K, Kim WC, Lee EJ, Koh JS, Park JR, Hahm JR, et al. A case of recurrent spontaneous hypoglycemia in a 73-year-old woman with congestive heart failure. Korean J Med. 2014; 87:205–8.
Article
14. Hedayati HA, Beheshti M. Profound spontaneous hypoglycaemia in congestive heart failure. Curr Med Res Opin. 1977; 4:501–4.
15. Khoury H, Daugherty T, Ehsanipoor K. Spontaneous hypoglycemia associated with congestive heart failure attributable to hyperinsulinism. Endocr Pract. 1998; 4:94–5.
Article
Full Text Links
  • JNC
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr