Blood Res.  2018 Sep;53(3):250-251. 10.5045/br.2018.53.3.250.

A misleading presentation of T cell/histiocyte rich B-cell lymphoma mimicking osteomyelitis

• Özpolat T
• Saka B
• Yonal-Hindilerden I
• Tascioglu
• Dogan O
• Nalcaci M

• KMID: 2429326
• DOI: http://doi.org/10.5045/br.2018.53.3.250

Abstract

No abstract available.

MeSH Terms

B-Lymphocytes*
Lymphoma, B-Cell*
Osteomyelitis*

Figure

• 

  Fig. 1 A triphasic bone scan scintigraphy showed increased late-phase activity in the frontal and parietal bones, right hip joint, right femoral condyle, right proximal, distal epiphyses of the tibia, and right tarsal bones.

• 

  Fig. 2 Bone marrow biopsy showed infiltration of T-cell/histiocyte-rich B-cell lymphoma (TC/HRBCL). (A) Scattered large atypical cells in a lymphohistiocytic background (H&E, ×1,000). (B) Scattered atypical B cells labeled with CD20 antibody, CD20 (×200). (C) Infiltration of reactive T cells with a nodular pattern labeled with CD3 antibody, CD3 (×200).

Reference

1. Unni KK, Hogendoorn PCW. WHO classification of tumours: pathology and genetics of tumours of soft tissue and bone. In : Fletcher CDM, Unni KK, Mertens F, editors. Malignant lymphoma. Lyon, France: IARC Press;2002. p. 306–308.

2. Choi JY, Hahn JS, Suh CO, Yang WI. Primary lymphoma of bone-survival and prognosis. Korean J Intern Med. 2002; 17:191–197.

3. Cabanela ME, Sim FH, Beabout JW, Dahlin DC. Osteomyelitis appearing as neoplasms. A diagnostic problem. Arch Surg. 1974; 109:68–72.

4. El Weshi A, Akhtar S, Mourad WA, et al. T-cell/histiocyte-rich B-cell lymphoma: clinical presentation, management and prognostic factors: report on 61 patients and review of literature. Leuk Lymphoma. 2007; 48:1764–1773.