Allergy Asthma Immunol Res.  2018 Jan;10(1):83-87. 10.4168/aair.2018.10.1.83.

Clinical Course of Chronic Spontaneous Urticaria in the Korean Adult Population

• Kim YS
• Park SH
• Han K
• Lee JH
• Kim NI
• Roh JY
• Seo SJ
• Song HJ
• Lee MG
• Choi JH
• Park YM

• KMID: 2428853
• DOI: http://doi.org/10.4168/aair.2018.10.1.83

Abstract

Knowledge of the clinical course of chronic spontaneous urticaria (CSU) remains unclear. The purpose of our study was to investigate the clinical course of CSU in the Korean adult population. Each patient in the CSU group who was defined by disease codes between 2003 and 2007 was tracked whether he or she went into remission or not until 2013. Kaplan-Meier survival analysis was carried out to analyze remission, and log-rank tests were performed for between-group comparisons. Demographic differences between subjects who went into remission 1 year after the initial diagnosis and those who did not were analyzed using χ² tests. A total of 13,969 subjects were included in the CSU group. The 1-, 2-, 3-, 4-, and 5-year remission rates of CSU were 21.5%, 33.0%, 38.9%, 42.6%, and 44.6%, respectively. The proportion of subjects in the 65+ age group (P=0.050) and with male gender (P=0.002) was significantly higher among subjects who did not go into remission 1 year after the initial diagnosis. Our study indicates that CSU could have a more persistent course than previously reported.

Keyword

Korea; urticarial; clinical course

MeSH Terms

Adult*
Diagnosis
Humans
Korea
Male
Urticaria*

Figure

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  Figure Kaplan-Meier survival analysis for the remission of CSU in the whole study group, and between-group analysis for gender and age. (A) The whole study group. (B) The male and female groups, (C) The 20-64 and 65+ age groups. CSU, chronic spontaneous urticaria.

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