Korean J Intern Med.  2018 Nov;33(6):1143-1149. 10.3904/kjim.2016.105.

Maternal and neonatal outcomes in Korean women with type 2 diabetes

• Jang HJ
• Kim HS
• Kim SH

• KMID: 2426399
• DOI: http://doi.org/10.3904/kjim.2016.105

Abstract

BACKGROUND/AIMS
The purpose of this study was to compare maternal and neonatal outcomes in Korean women with type 2 diabetes and nondiabetic controls.
METHODS
We performed a retrospective survey of 200 pregnancies in women with type 2 diabetes (n = 100) and nondiabetic controls (n = 100) who delivered from 2003 to 2010 at Cheil General Hospital & Women's Healthcare Center, Korea. We compared maternal characteristics as well as maternal and neonatal outcomes between groups matched by age, pre-pregnancy weight, body mass index, parity, and gestational age at delivery.
RESULTS
The number of infants that were small for gestational age and the rate of major congenital malformations were not significantly different. However, women with type 2 diabetes showed a slightly higher risk for primary caesarean section (35.0% vs. 18.0%, p = 0.006) as well as pre-eclampsia (10.0% vs. 2.0%, p = 0.017), infections during pregnancy (26.0% vs. 2.0%, p < 0.001), neonatal weight (3,370 ± 552.0 vs. 3,196 ± 543.3, p = 0.025), large for gestational age (22.0% vs. 9.0%, p = 0.011), and macrosomia (15.0% vs. 5.0%, p = 0.018) compared to nondiabetic controls.
CONCLUSIONS
Maternal and neonatal outcomes for women with type 2 diabetes were worse than those for nondiabetic controls. Diabetic women have a higher risk for primary caesarean section, pre-eclampsia, infections during pregnancy, large neonatal birth weight, large for gestational age, and macrosomia.

Keyword

Diabetes mellitus, type 2; Pregnancy outcome

MeSH Terms

Birth Weight
Body Weight
Cesarean Section
Delivery of Health Care
Diabetes Mellitus, Type 2
Female
Gestational Age
Hospitals, General
Humans
Infant
Korea
Parity
Pre-Eclampsia
Pregnancy
Pregnancy Outcome
Retrospective Studies