Korean J Dermatol.  1997 Dec;35(6):1254-1257.

A Case of Sarcoidosis with Foreign Body within Granuloma

• Kim HS
• Kim YC
• Park HJ
• Cinn YW

Abstract

Sarcoidosis is a multisystemie disease of unknown cause eharacterized by the formation of noncaseating granulomas that may involve any organ, but the most common sites are the lungs, lyrnph nodes, skin, and eyes. We report a case of sarc ( idosis which may be caused by a foreign body reaction. A 49-year-old women was presented with violet colored, scaly papules on the back and subcutaneous nodules on the left index finger, which had been present for 6 months. A biopsy of a nodule on the left index finger revealed noncaseating epithelioid cell granuloma throughout the dermis with foreign body in the center of the granuloma. Under the polarized light microscopy, tiny particles of foreign material were more obvious. We think that foreign material may actually serve as a nidus for granuloma formation in sarcoidosis.

Keyword

Sarcoidosis; Foreign body

MeSH Terms

Biopsy
Dermis
Epithelioid Cells
Female
Fingers
Foreign Bodies*
Foreign-Body Reaction
Granuloma*
Humans
Lung
Microscopy, Polarization
Middle Aged
Sarcoidosis*
Skin
Viola