Clin Endosc.  2013 Jul;46(4):395-398.

Biliary-Pancreatic Endoscopic and Surgical Procedures in Patients under Dual Antiplatelet Therapy: A Single-Center Study

• Abdel Samie A
• Stumpf M
• Sun R
• Theilmann

Abstract

BACKGROUND/AIMS
Dual antiplatelet therapy has to be used for at least 1 month after placement of bare metal coronary stents and for a minimum of 1 year after placement of drug eluting stents. Because of the higher risk of bleeding, guidelines strongly recommend to delay elective surgery until dual antiplatelet therapy is ended. However, no data are available regarding the bleeding risk in patients on combined aspirin/clopidogrel therapy undergoing surgical or high-risk endoscopic procedures.
METHODS
We retrospectively analyzed the medical reports of patients on dual antiplatelet therapy, the patients who had to undergo emergency biliary-pancreatic surgery or endoscopic retrograde cholangiography with endoscopic sphincterotomy while in our unit between January 2009 and July 2012.
RESULTS
In our series, biliary-pancreatic surgical and endoscopic procedures were safely performed in 11 consecutive patients on dual antiplatelet therapy with no evidence of bleeding.
CONCLUSIONS
In emergency, surgical and high risk endoscopic procedures may be performed in patients on dual antiplatelet therapy.

Keyword

Dual antiplatelet therapy; Sphincterotomy, endoscopic; General surgery

MeSH Terms

Cholangiography
Drug-Eluting Stents
Emergencies
Hemorrhage
Humans
Retrospective Studies
Sphincterotomy, Endoscopic
Stents

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