Clin Endosc.  2013 Jul;46(4):337-341.

A Review of Current Disinfectants for Gastrointestinal Endoscopic Reprocessing

Affiliations
  • 1Department of Internal Medicine, KEPCO Medical Center, Seoul, Korea.
  • 2Division of Gastroenterology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea. jyjang@khu.ac.kr
  • 3Division of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of Medicine, Seoul, Korea.
  • 4Department of Internal Medicine, Dongguk University College of Medicine, Gyeongju, Korea.
  • 5Department of Internal Medicine, Dongguk University Graduate School of Medicine, Goyang, Korea.
  • 6Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.
  • 7Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.

Abstract

Gastrointestinal endoscopy is gaining popularity for diagnostic and therapeutic purposes. However, concerns over endoscope-related nosocomial infections are increasing, together with interest by the general public in safe and efficient endoscopy. For this reason, reprocessing the gastrointestinal endoscope is an important step for effective performance of endoscopy. Disinfectants are essential to the endoscope reprocessing procedure. Before selecting an appropriate disinfectant, their characteristics, limitations and means of use must be fully understood. Herein, we review the characteristics of several currently available disinfectants, including their uses, potency, advantages, and disadvantages. Most disinfectants can be used to reprocess gastrointestinal endoscopes if the manufacturer's guidelines are followed. The selection and use of a suitable disinfectant depends on the individual circumstances of each endoscopy suite.

Keyword

Endoscopy, gastrointestinal; Disinfectants; Reprocessing

MeSH Terms

Cross Infection
Disinfectants
Endoscopes
Endoscopes, Gastrointestinal
Endoscopy
Endoscopy, Gastrointestinal
Disinfectants

Reference

1. Nelson DB. Recent advances in epidemiology and prevention of gastrointestinal endoscopy related infections. Curr Opin Infect Dis. 2005; 18:326–330. PMID: 15985829.
Article
2. Spach DH, Silverstein FE, Stamm WE. Transmission of infection by gastrointestinal endoscopy and bronchoscopy. Ann Intern Med. 1993; 118:117–128. PMID: 8416308.
Article
3. Nelson DB, Barkun AN, Block KP, et al. Technology status evaluation report Transmission of infection by gastrointestinal endoscopy. May 2001. Gastrointest Endosc. 2001; 54:824–828. PMID: 11726877.
4. Beilenhoff U, Neumann CS, Rey JF, et al. ESGE-ESGENA Guideline: cleaning and disinfection in gastrointestinal endoscopy. Endoscopy. 2008; 40:939–957. PMID: 19009486.
Article
5. Favero MS, Bond WW. Disinfection of medical and surgeical materials. In : Block SS, editor. Disinfection, Sterilization, and Preservation. 5th ed. Philadelphia: Lippincott Williams & Wilkins;2001. p. 881–917.
6. Kim HJ. KFDA-cleared disinfectants in gastrointestinal endoscopy. Korean J Gastrointest Endosc. 2010; 40:50–52.
7. U.S. Food and Drug Administration. FDA-cleared sterilants and high level disinfectants with general claims for processing reusable medical and dental devices: March 2009 [Internet]. Silver Spring: U.S. Food and Drug Administration;2009. updated 2009 Apr 26. cited 2012 Feb 2. Available from: http://www.fda.gov/MedicalDevices/DeviceRegulationandGuidance/ReprocessingofSingle-UseDevices/ucm133514.htm.
8. The Korean Society of Gastrointestinal Endoscopy Disinfection Management Committee. Guidebook for Cleaning and Disinfecting Gastrointestinal Endoscopes. 1st ed. Seoul: Medbook;2012. p. 93.
9. Society of Gastroenterology Nurses and Associates. SGNA guidelines for nursing care of the patient receiving sedation and analgesia in the gastrointestinal endoscopy setting. Gastroenterol Nurs. 2000; 23:125–129. PMID: 11235444.
10. Walter V. Reprocessing of flexible gastrointestinal endoscopes: an American Society for Gastrointestinal Endoscopy white paper. Gastroenterol Nurs. 1996; 19:109–112. PMID: 8716956.
11. Rutala WA. Association for Professionals in Infection Control and Epidemiology, Inc. APIC guideline for selection and use of disinfectants. 1994, 1995, and 1996 APIC Guidelines Committee. Am J Infect Control. 1996; 24:313–342. PMID: 8870916.
12. Griffiths PA, Babb JR, Fraise AP. Mycobactericidal activity of selected disinfectants using a quantitative suspension test. J Hosp Infect. 1999; 41:111–121. PMID: 10063473.
Article
13. Axon AT, Banks J, Cockel R, Deverill CE, Newmann C. Disinfection in upper-digestive-tract endoscopy in Britain. Lancet. 1981; 1:1093–1094. PMID: 6112457.
Article
14. Cowan RE, Manning AP, Ayliffe GA, et al. British Society of Gastroenterology Endoscopy Committee. Aldehyde disinfectants and health in endoscopy units. Gut. 1993; 34:1641–1645. PMID: 8244157.
Article
15. Hanson JM, Plusa SM, Bennett MK, Browell DA, Cunliffe WJ. Glutaraldehyde as a possible cause of diarrhoea after sigmoidoscopy. Br J Surg. 1998; 85:1385–1387. PMID: 9782020.
Article
16. West AB, Kuan SF, Bennick M, Lagarde S. Glutaraldehyde colitis following endoscopy: clinical and pathological features and investigation of an outbreak. Gastroenterology. 1995; 108:1250–1255. PMID: 7698592.
Article
17. Jonas G, Mahoney A, Murray J, Gertler S. Chemical colitis due to endoscope cleaning solutions: a mimic of pseudomembranous colitis. Gastroenterology. 1988; 95:1403–1408. PMID: 3169504.
Article
18. Jordan SL. The correct use of glutaraldehyde in the healthcare environment. Gastroenterol Nurs. 1995; 18:143–145. PMID: 7654811.
Article
19. Burkart J. NIOSH Health Hazard Evaluation Report. Washington, DC: U.S. Dept. of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health;1991.
20. Gregory AW, Schaalje GB, Smart JD, Robison RA. The mycobactericidal efficacy of ortho-phthalaldehyde and the comparative resistances of Mycobacterium bovis, Mycobacterium terrae, and Mycobacterium chelonae. Infect Control Hosp Epidemiol. 1999; 20:324–330. PMID: 10349948.
Article
21. Alfa MJ, Sitter DL. In-hospital evaluation of orthophthalaldehyde as a high level disinfectant for flexible endoscopes. J Hosp Infect. 1994; 26:15–26. PMID: 7910179.
Article
22. Rideout K, Teschke K, Dimich-Ward H, Kennedy SM. Considering risks to healthcare workers from glutaraldehyde alternatives in high-level disinfection. J Hosp Infect. 2005; 59:4–11. PMID: 15571847.
Article
23. Kim KJ. Pros and cons of various endoscopic disinfectants. Korean J Gastrointest Endosc. 2009; 39(Suppl):97S–100S.
24. Fraise AP. Choosing disinfectants. J Hosp Infect. 1999; 43:255–264. PMID: 10658801.
Article
25. Kim H. Characteristics and types of disinfectants. Korean J Gastrointest Endosc. 2010; 41:198–201.
26. Lee JH, Rhee PL, Kim JH, et al. Efficacy of electrolyzed acid water in reprocessing patient-used flexible upper endoscopes: comparison with 2% alkaline glutaraldehyde. J Gastroenterol Hepatol. 2004; 19:897–903. PMID: 15242493.
Article
27. Urata M, Isomoto H, Murase K, et al. Comparison of the microbicidal activities of superoxidized and ozonated water in the disinfection of endoscopes. J Int Med Res. 2003; 31:299–306. PMID: 12964505.
Article
28. Rossi-Fedele G, Guastalli AR, Doğramacı EJ, Steier L, De Figueiredo JA. Influence of pH changes on chlorine-containing endodontic irrigating solutions. Int Endod J. 2011; 44:792–799. PMID: 21658076.
Article
29. BSG Endoscopy Committee Working Party. Cleaning and disinfection of equipment for gastrointestinal endoscopy. Report of a Working Party of the British Society of Gastroenterology Endoscopy Committee. Gut. 1998; 42:585–593. PMID: 9616326.
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