Hip Pelvis.  2017 Jun;29(2):120-126. 10.5371/hp.2017.29.2.120.

Pelvic Insufficiency Fracture in Severe Osteoporosis Patient

Affiliations
  • 1Department of Orthopaedic Surgery, College of Medicine, Chosun University, Gwangju, Korea. shalee@chosun.ac.kr

Abstract

PURPOSE
To evaluate clinical features and the effect of parathyroid hormone (PTH) on treatment outcomes of patients with pelvic insufficiency fractures.
MATERIALS AND METHODS
Fifteen patients diagnosed with pelvic insufficiency fractures were evaluated retrospectively. All patients had osteoporosis with mean lumbar T score of −3.9 (range, −3.1 to −6.4) and the mean age was 76.5 years. In all cases, simple radiography and computed tomography was used for final diagnosis; additional magnetic resonance imaging and technetium bone scans were used to confirm the diagnosis in 2 and 6 patients, respectively. Initial conservative treatment was used in all cases; treatment with PTH was applied in 5 cases. Radiological follow-up was done every 4 weeks up to 6 months and every 3 months thereafter. Symptom improvement was measured using visual analogue scale (VAS) score.
RESULTS
Fractures were located: i) sacrum and pubis (9 cases), ii) isolated sacrum (4 cases) and iii) isolated pubis (2 cases). One case showed fracture displacement and pain aggravation at 4 week follow-up which was treated with percutaneous sacro-iliac fixation using cannulated screws. Duration of bone union was significantly shorter in the patients who used PTH (P<0.05). VAS scores were also lower in the group treated with PTH; however, statistical significance was not reached.
CONCLUSION
In patients with osteoporosis, a pelvic insufficiency fracture should be considered if pain is experienced in the pelvic area in the absence of major trauma. While nonoperatic has been shown to be sufficient for treatment, our study shows that PTH therapy shortens treatment period and could be a favorable treatment option.

Keyword

Insufficiency fractures; Osteoporosis; Parathyroid hormone; Pelvic fracture; Sacral fracture

MeSH Terms

Diagnosis
Follow-Up Studies
Fractures, Stress*
Humans
Magnetic Resonance Imaging
Osteoporosis*
Parathyroid Hormone
Pubic Bone
Radiography
Retrospective Studies
Sacrum
Technetium
Parathyroid Hormone
Technetium

Figure

  • Fig. 1 Radiographs of a 82-year-old female patient. (A) Simple radiography shows left pubis superior and inferior ramus fracture. (B) Thorax and abdomen computed tomography shows multiple spine compression fracture (T3, T7, L1-L3).

  • Fig. 2 Radiographs of a 73-year-old female patient. (A, B) Simple radiography and computed tomography shows pelvic bone insufficiency fracture. (C) Bone scan shows Honda sign that means pelvic insufficiency fracture.

  • Fig. 3 Radiographs of a 74-year-old female patient. (A) Simple radiography shows right pubis superior and inferior ramus insufficiency fracture. (B) Forteo® (Eli Lilly) injected during 4 months and it shows complete bone union on simple radiography.


Reference

1. Morris CD, Einhorn TA. Bisphosphonates in orthopaedic surgery. J Bone Joint Surg Am. 2005; 87:1609–1618.
Article
2. Rodan GA, Reszka AA. Osteoporosis and bisphosphonates. J Bone Joint Surg Am. 2003; 85-A:Suppl 3. 8–12.
Article
3. Koh HS, Kang YK, Lee HY, et al. Insufficiency fractures of the femoral shaft associated with osteoporosis. J Korean Fract Soc. 2004; 17:19–24.
Article
4. Lourie H. Spontaneous osteoporotic fracture of the sacrum. An unrecognized syndrome of the elderly. JAMA. 1982; 248:715–717.
Article
5. Finiels H, Finiels PJ, Jacquot JM, Strubel D. [Fractures of the sacrum caused by bone insufficiency. Meta-analysis of 508 cases]. Presse Med. 1997; 26:1568–1573. French.
6. Rommens PM, Hofmann A. Comprehensive classification of fragility fractures of the pelvic ring: Recommendations for surgical treatment. Injury. 2013; 44:1733–1744.
Article
7. Weber M, Hasler P, Gerber H. Insufficiency fractures of the sacrum Twenty cases and review of the literature. Spine (Phila Pa 1976). 1993; 18:2507–2512.
8. Melton LJ 3rd, Sampson JM, Morrey BF, Ilstrup DM. Epidemiologic features of pelvic fractures. Clin Orthop Relat Res. 1981; (155):43–47.
Article
9. Blomlie V, Rofstad EK, Talle K, Sundfør K, Winderen M, Lien HH. Incidence of radiation-induced insufficiency fractures of the female pelvis: evaluation with MR imaging. AJR Am J Roentgenol. 1996; 167:1205–1210.
Article
10. Grangier C, Garcia J, Howarth NR, May M, Rossier P. Role of MRI in the diagnosis of insufficiency fractures of the sacrum and acetabular roof. Skeletal Radiol. 1997; 26:517–524.
Article
11. Lyders EM, Whitlow CT, Baker MD, Morris PP. Imaging and treatment of sacral insufficiency fractures. AJNR Am J Neuroradiol. 2010; 31:201–210.
Article
12. Lin JT, Lane JM. Sacral stress fractures. J Womens Health (Larchmt). 2003; 12:879–888.
Article
13. Newhouse KE, el-Khoury GY, Buckwalter JA. Occult sacral fractures in osteopenic patients. J Bone Joint Surg Am. 1992; 74:1472–1477.
14. Leroux JL, Denat B, Thomas E, Blotman F, Bonnel F. Sacral insufficiency fractures presenting as acute low-back pain. Biomechanical aspects. Spine (Phila Pa 1976). 1993; 18:2502–2506.
15. Babayev M, Lachmann E, Nagler W. The controversy surrounding sacral insufficiency fractures: to ambulate or not to ambulate? Am J Phys Med Rehabil. 2000; 79:404–409.
16. Karlsson MK, Obran K, Josefsson PO. Osteoporotic fractures. In : Rockwood CA, Green DP, Bucholz RW, editors. Rockwood and Green's fractures in adults. 6th ed. Philadelphia: Lippincott-Williams & Wilkins;2005. p. 614–641.
17. Chae SU, Kim YJ, Yang JH, Lee JW. Usefulness of kyphoplasty in sacral insufficiency fracture: a case report. J Korean Fract Soc. 2011; 24:174–177.
Article
18. Frey ME, Depalma MJ, Cifu DX, Bhagia SM, Carne W, Daitch JS. Percutaneous sacroplasty for osteoporotic sacral insufficiency fractures: a prospective, multicenter, observational pilot study. Spine J. 2008; 8:367–373.
Article
19. Routt ML Jr, Simonian PT. Closed reduction and percutaneous skeletal fixation of sacral fractures. Clin Orthop Relat Res. 1996; (329):121–128.
20. Tsiridis E, Upadhyay N, Gamie Z, Giannoudis PV. Percutaneous screw fixation for sacral insufficiency fractures: a review of three cases. J Bone Joint Surg Br. 2007; 89:1650–1653.
21. Rommens PM, Dietz SO, Ossendorf C, Pairon P, Wagner D, Hofmann A. Fragility fractures of the pelvis: should they be fixed? Acta Chir Orthop Traumatol Cech. 2015; 82:101–112.
22. Hodsman AB, Bauer DC, Dempster DW, et al. Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its use. Endocr Rev. 2005; 26:688–703.
Article
23. Ha YC, Lee YK, Min BW. Medical treatment of atypical femoral fracture. J Korean Orthop Assoc. 2013; 48:180–184.
Article
Full Text Links
  • HP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr