J Korean Ophthalmol Soc.  2018 Oct;59(10):922-929. 10.3341/jkos.2018.59.10.922.

The Incidence and Risk Factors of Epiretinal Membrane in a Screened Korean Population

• Kim SH
• Song SJ
• Bae JH

• KMID: 2422580
• DOI: http://doi.org/10.3341/jkos.2018.59.10.922

Abstract

PURPOSE
To determine the incidence of idiopathic epiretinal membrane (ERM) and its risk factors in Korean adults.
METHODS
A total of 16,495 participants (≥50 years of age) who had at least two examinations from January 2006 to December 2016 were included in this study. The incidence of idiopathic ERM was determined and age-standardized to the 2010 Korean Census.
RESULTS
Idiopathic ERM developed in 391 of 15,399 participants who had no previous ERM in either eye at the baseline examination. The overall age-standardized incidence was 2.18% (95% confidence interval [CI], 1.89-2.38), including 1.39% with cellophane macular reflex and 0.79% with preretinal macular fibrosis. Multivariate Cox regression analyses revealed that the factor related to the development of idiopathic ERM was obesity (body mass index >25 kg/m2; adjusted hazard ratio, 0.77; 95% CI, 0.60-0.97) after adjusting for confounding factors.
CONCLUSIONS
The incidence of idiopathic ERM in Korean adults was lower than that of other ethnic studies. Further studies are needed to confirm the inverse relationship between obesity and the incidence of ERM in this population.

Keyword

Epiretinal membrane; Incidence; Koreans; Risk factors

MeSH Terms

Adult
Asian Continental Ancestry Group
Cellophane
Censuses
Epiretinal Membrane*
Fibrosis
Humans
Incidence*
Obesity
Reflex
Risk Factors*
Cellophane

Figure

• 

  Figure 1 Representative fundus photograph of cellophane macular reflex (CMR). Right fundus of participant with CMR only, best seen nasal to fovea.

• 

  Figure 2 Preretinal macular fibrosis (PMF). Left fundus of participant with PMF, with vertical folds around fovea.

• 

  Figure 3 Study flow diagram. Describing subjects which included for analysis.

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