J Korean Med Sci.  2018 Oct;33(42):e267. 10.3346/jkms.2018.33.e267.

Coronary Artery Bypass Grafting with Arterial Grafts in Patients with Kawasaki Disease Affecting the Coronary Artery: a Korean Single-Center Study

• Jeong DS
• Han W
• Lee YT
• Kim WS
• Song J
• Kang IS
• Park PW

• KMID: 2422090
• DOI: http://doi.org/10.3346/jkms.2018.33.e267

Abstract

BACKGROUND
This study aimed to review the long-term clinical outcomes and graft patency of coronary artery bypass grafting (CABG) using arterial grafts in patients with Kawasaki disease (KD) affecting the coronary artery.
METHODS
Twenty patients with KD who underwent CABG from January 2002 to June 2014 were enrolled. There were 4 male (20%) and 16 female (80%) patients with ages at operation ranging from 2 to 42 years (median, 17.5 years). Our routine operative strategy was off-pump CABG with arterial grafts. The mean follow-up duration was 59.5 ± 48.5 months (range, 1-159 months). Coronary angiogram or computed tomography angiogram was used to evaluate graft patency in 16 patients (80%).
RESULTS
All patients survived CABG without late mortality. Left internal thoracic arteries were used in 19 patients, while right internal thoracic arteries were used in 10 patients. Right gastroepiploic arteries were used in 3 patients, and a saphenous vein graft (SVG) was used in 1 patient. Among the 20 patients, 2 patients underwent coronary reintervention with balloon angioplasty because of graft failure. Two patients underwent coronary reintervention because of new obstructive lesions that were not significant at the time of the initial operation. Patency rates at 5 and 10 years were 94% and 87%, respectively. The rate of freedom from coronary reintervention at 10 years was 82%.
CONCLUSION
Off-pump CABG with mainly arterial graft revascularization may be considered a good surgical option for coronary lesions caused by KD.

Keyword

Coronary Artery Bypass Grafting; Kawasaki Disease; Graft

MeSH Terms

Angioplasty, Balloon
Coronary Artery Bypass*
Coronary Vessels*
Female
Follow-Up Studies
Freedom
Gastroepiploic Artery
Humans
Male
Mammary Arteries
Mortality
Mucocutaneous Lymph Node Syndrome*
Saphenous Vein
Transplants