Korean J Ophthalmol.  2018 Oct;32(5):376-381. 10.3341/kjo.2017.0123.

Posterior Vitreous Structures Evaluated by Swept-source Optical Coherence Tomography with En Face Imaging

• Park JW
• Lee JE
• Pak KY

• KMID: 2422067
• DOI: http://doi.org/10.3341/kjo.2017.0123

Abstract

PURPOSE
To evaluate posterior vitreous structures using swept-source (SS) optical coherence tomography (OCT) with en face imaging.
METHODS
We retrospectively reviewed OCT images of healthy individuals who did not have intra-ocular disease. We obtained high-definition horizontal and vertical line scans crossing the fovea and 3D scans using SS-OCT, with the 3D scan centered between the fovea and the optic-nerve head. An enhanced vitreous visualization function was used to highlight vitreous structures. En face mode was used to measure the area of Martegiani (AM) and bursa premacularis (BP). We performed all measurements using a built-in function of the viewing software.
RESULTS
We enrolled 24 eyes from 12 healthy individuals. The mean patient age was 28.7 ± 4.6 years (range, 24 to 39 years). The mean AM and BP areas were 5.73 ± 0.88 and 18.76 ± 6.95 mm2, respectively. In en face imaging, AM shape was most frequently a vertical oval (18 / 22, 81.8%), while the predominant BP shape was round (16 / 20, 80.0%). AM was in contact with the optic disc, either at the temporal-disc margin (13 eyes, 59.1%) or the nasal optic-disc margin (9 eyes, 40.9%).
CONCLUSIONS
Posterior vitreous structures, such as AM and BP, were readily visualized using en face imaging with SS-OCT. Investigating normal vitreous configuration might help in understanding changes in vitreous structures associated with retinal pathology.

Keyword

Area of Martegiani; Bursa premacularis; En face; Swept-source optical coherence tomography; Vitreous body

MeSH Terms

Head
Humans
Pathology
Retinaldehyde
Retrospective Studies
Tomography, Optical Coherence*
Vitreous Body
Retinaldehyde

Figure

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  Fig. 1 (A) Twelve-millimetre horizontal line scan centered at the fovea: the enhanced vitreous visualization function was turned on, and the vitreous structure is highlighted. Horizontal and vertical arrows indicate width and central thickness of bursa premacularis, respectively. (B) Twelve-millimetre vertical line scan. (C) En face image generated from a 12 × 9-mm 3D cube scan.

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  Fig. 2 Representative horizontal cross section images of bursa premacularis. (A) Boat shape, (B) wedge shape, and (C) irregular shape.

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  Fig. 3 Spearman correlation analysis of the optic disc area and the area of Martegiani.

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  Fig. 4 Spatial relationship between optic disc margin and area of Martegiani (AM) margin. (A) The AM margin shares its temporal border with the optic disc. (B) The AM margin shares its nasal border with the optic disc.

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