Allergy Asthma Respir Dis.  2018 Sep;6(Suppl 1):S77-S84. 10.4168/aard.2018.6.S1.S77.

Overview and challenges of current genetic research on allergic diseases in Korean children

Affiliations
  • 1Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. mhsohn@yuhs.ac

Abstract

Since Cookson et al. first reported the association of atopy with chromosome 11q13 in 1989, there have been numerous studies of genetics for allergic diseases. Their aim is to identify genetic factors modifying susceptibility to allergic diseases, determining the severity of disease in affected individuals and affecting the response to treatment. With these efforts, allergic diseases can be termed complex genetic disorders, defined as disorders that have numerous contributing genes, each having variable degrees of involvement in any given individual. This review aims to provide information on the current state of genetic research in Korean pediatric allergic diseases.

Keyword

Genetics; Korea; Pediatrics; Allergy; Asthma
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