Tuberc Respir Dis.  2018 Oct;81(4):311-318. 10.4046/trd.2017.0081.

Body Mass Index as a Predictor of Acute Kidney Injury in Critically Ill Patients: A Retrospective Single-Center Study

• Ju S
• Lee TW
• Yoo JW
• Lee SJ
• Cho YJ
• Jeong YY
• Lee JD
• Kim JY
• Lee GD
• Kim HC

• KMID: 2420565
• DOI: http://doi.org/10.4046/trd.2017.0081

Abstract

BACKGROUND
The aim of this study was to examine the influence of body mass index (BMI) on the development of acute kidney injury (AKI) in critically ill patients in intensive care unit (ICU).
METHODS
Data of patients admitted to medical ICU from December 2011 to May 2014 were retrospectively analyzed. Patients were classified into three groups according to their BMI: underweight ( < 18.5 kg/m2), normal (18.5-24.9 kg/m2), and overweight (≥25 kg/m2). The incidence of AKI was compared among these groups and factors associated with the development of AKI were analyzed. AKI was defined according to the Risk, Injury, Failure, Loss of kidney function, and End-stage (RIFLE) kidney disease criteria.
RESULTS
A total of 468 patients were analyzed. Their mean BMI was 21.5±3.9 kg/m2, including 102 (21.8%) underweight, 286 (61.1%) normal-weight, and 80 (17.1%) overweight patients. Overall, AKI occurred in 82 (17.5%) patients. The overweight group had significantly (p < 0.001) higher incidence of AKI (36.3%) than the underweight (9.8%) or normal group (15.0%). In addition, BMI was significantly higher in patients with AKI than that in those without AKI (23.4±4.2 vs. 21.1±3.7, p < 0.001). Multivariate analysis showed that BMI was significantly associated with the development of AKI (odds ratio, 1.893; 95% confidence interval, 1.224-2.927).
CONCLUSION
BMI may be associated with the development of AKI in critically ill patients.

Keyword

Body Mass Index; Acute Kidney Injury; Intensive Care Unit

MeSH Terms

Acute Kidney Injury*
Body Mass Index*
Critical Illness*
Humans
Incidence
Intensive Care Units
Kidney
Kidney Diseases
Multivariate Analysis
Overweight
Retrospective Studies*
Thinness

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