Ann Lab Med.  2019 Jan;39(1):96-98. 10.3343/alm.2019.39.1.96.

First Case of Plasma Cell Myeloma With Brown Tumor Features Unrelated to Hyperparathyroidism

• Kim H
• Kim K
• Cho SR
• Kim HJ
• Kim SH

• KMID: 2420278
• DOI: http://doi.org/10.3343/alm.2019.39.1.96

Abstract

No abstract available.

MeSH Terms

Hyperparathyroidism*
Multiple Myeloma*
Plasma Cells*
Plasma*

Figure

• 

  Fig. 1 Features of bone marrow aspiration and biopsy. (A, B) Bone marrow aspirate showing increased plasma cells (black arrows) with markedly increased osteoclast clusters (Wright-Giemsa stain, ×100 & ×400). A multinucleated osteoclast is magnified in right upper section of Fig. 1A. (C, D) Bone marrow biopsy with tunneling feature as well as interstitial hemorrhage and woven bone formation following trabecular destruction and increase in osteoclast proliferation (hematoxylin & eosin, ×100 & ×400). (E) Immunohistochemical staining was positive for CD138 in bone marrow biopsy. (F) Ig kappa light chain on malignant plasma cells. Interstitial hemorrhage was observed in the form of crystals (black arrows) after Ig kappa light chain staining (×400).

Reference

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