Yonsei Med J.  2017 Sep;58(5):1047-1050. 10.3349/ymj.2017.58.5.1047.

Prevalence and Clinical Characteristics of Local Allergic Rhinitis to House Dust Mites

• Jung CG
• Lee JH
• Ban GY
• Park HS
• Shin YS

• KMID: 2418944
• DOI: http://doi.org/10.3349/ymj.2017.58.5.1047

Abstract

Local allergic rhinitis (LAR) is a localized nasal allergic response in the absence of systemic atopy. The aim of this study was to evaluate the prevalence and clinical characteristics of LAR in Korean rhinitis patients compared to allergic rhinitis (AR) and non-allergic rhinitis (NAR). A total of 304 rhinitis patients were enrolled from November 2014 to March 2016. A skin prick test, serum total and specific immunoglobulin E, and a nasal provocation test (NPT) with house dust mite (HDM) were performed on all patients. Subjects also documented changes in rhinitis symptoms before and after NPT. Seventy-four patients with nasal hyper-reactivity and 80 patients with subclinical allergy were excluded. AR was diagnosed in 69 (46.0%) patients, NAR in 75 (50.0%) patients, and LAR to HDM in 6 (4.0%) patients. The average medication score and disease duration of each group were 14.5 points and 77.6 months in AR, 12.1 point and 51.1 months in NAR, and 17.7 point and 106.0 months in LAR, respectively. There were no significant differences in the baseline nasal symptom score of the three groups. However, after NPT with HDM, the score of rhinitis, itching, and obstructive were 4.83±1.47 vs. 1.95±2.53, 3.00±2.10 vs. 1.45±2.06, and 5.50±1.38 vs. 2.57±2.84 in LAR and NAR, respectively (p<0.05). LAR patients had longer duration of disease and tended to be older and have higher medication score than other rhinitis patients.

Keyword

Local allergic rhinitis; nasal provocation test; house dust mite

MeSH Terms

Adult
Animals
Female
Humans
Male
Nasal Provocation Tests
Prevalence
Pyroglyphidae/*physiology
Rhinitis, Allergic/*epidemiology/*parasitology/pathology
Skin Tests
Visual Analog Scale

Figure

• 

  Fig. 1 Change of nasal symptom patterns assessed by the Visual Analogue Scale (VAS). Data are expressed as mean±standard deviation. *p<0.05, †p<0.01 compared to each group. AR, allergic rhinitis; LAR, local allergic rhinitis; NAR, non-allergic rhinitis; Baseline, nasal symptoms at baseline; Saline NPT, nasal symptoms after NPT with saline; HDM NPT, nasal symptoms after NPT with Dermatophagoides farinae; NPT, nasal provocation test.

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