Int Neurourol J.  2018 Jun;22(2):77-82. 10.5213/inj.1836120.060.

Overactive Bladder is a Distress Symptom in Heart Failure

• Son YJ
• Kwon BE

• KMID: 2417779
• DOI: http://doi.org/10.5213/inj.1836120.060

Abstract

The prevalence of Heart failure (HF) is expected to increase worldwide with the aging population trend. The numerous symptoms of and repeated hospitalizations for HF negatively affect the patient's quality of life and increase the patient's economic burden. Up to 50% of patients with HF suffer from urinary incontinence (UI) and an overactive bladder (OAB). However, there are limited data about the relationship between UI, OAB, and HF. The association between HF and urinary symptoms may be directly attributable to worsening HF pathophysiology. A comprehensive literature review was conducted for all publications between January 2000 and November 2017 using the PubMed, Embase, and Cochrane databases. HF represents a major and growing public health problem, with an increased risk of UI and an OAB as comorbidities. Possible effects of HF on urinary problems may be mediated by the prescription of medications for symptomatic relief. Although diuretics are typically used to relieve congestion, and angiotensin-converting enzyme inhibitors and angiotensin receptor blockers improve survival, these classes of drugs have been suggested to worsen urinary symptoms in the presence of HF. Further research is required to understand the impact of UI and an OAB on the HF illness trajectory.

Keyword

Heart failure; Urinary incontinence; Overactive urinary bladder; Prevalence; Comorbidity

MeSH Terms

Aging
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Comorbidity
Diuretics
Estrogens, Conjugated (USP)
Heart Failure*
Heart*
Hospitalization
Humans
Prescriptions
Prevalence
Public Health
Quality of Life
Urinary Bladder, Overactive*
Urinary Incontinence
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Diuretics
Estrogens, Conjugated (USP)