J Cancer Prev.  2018 Jun;23(2):93-98. 10.15430/JCP.2018.23.2.93.

The Impact of Implant Location on Breast Cancer Characteristics in Previously Augmented Patients: A Systematic Literature Analysis

• Azzi AJ
• Gornitsky
• Viezel-Mathieu A
• Lessard L

• KMID: 2417373
• DOI: http://doi.org/10.15430/JCP.2018.23.2.93

Abstract

BACKGROUND
There is a paucity of data comparing the oncologic properties of breast cancer among patients previously having undergone breast augmentation in either the subglandular or subpectoral planes. The objective of the present systematic review was to evaluate whether implant location influenced the characteristics of breast tumors in previously augmented women.
METHODS
A systematic literature search was performed to identify relevant articles reporting tumor characteristics in augmented patients. The search included published articles in three electronic databases; Ovid MEDLINE, EMBASE, and PubMed. Comparative studies (subglandular vs. subpectoral) were included.
RESULTS
Analysis of data pooled from the included studies showed that subglandular implants had a higher frequency of tumors between 2 to 5 cm (26.5% vs. 9.9%, P = 0.0130). Subglandular implants also had a higher frequency of stage 2 tumors (42.9% vs. 23.7%, P = 0.0308). There was no significant difference in lymphovascular invasion between the 2 groups. These results of this systematic review suggest that the prognosis of patients undergoing augmentation is unaffected by implant location (subpectoral vs. subglandular).
CONCLUSIONS
With the absence of large randomized controlled trials, our study provides surgeons with an evidence-based reference to improve informed consent with regards to implant placement.

Keyword

Breast Implants; Breast Neoplasms; Mammography

MeSH Terms

Breast Implants
Breast Neoplasms*
Breast*
Female
Humans
Informed Consent
Mammography
Prognosis
Surgeons